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Antimicrobials

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ESCMID and ASM’s review need for new strategies and tactics to fight antimicrobial resistance

11 October 2016 | By Niamh Louise Marriott, Digital Content Producer

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the American Society for Microbiology (ASM) have just closed a joint conference in Vienna, which aimed to help researchers accelerate the development of new antimicrobials and to shed light on the challenges associated with antimicrobial resistance.

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Flow cytometry: breaking bottlenecks in drug discovery and development

20 September 2016 | By Pooja Sharma, Pushpanathan Muthuirulan

The discovery and development of novel drug candidates is a highly complex, time-consuming and expensive process. Pharmaceutical scientists and clinicians should, therefore, reevaluate and modify the existing standard platforms and increase their uptake of robust advanced technologies such as flow cytometry to overcome the bottlenecks in these processes...

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ESCMID-ASM to review antimicrobial development process

27 June 2016 | By European Society of Clinical Microbiology and Infectious Diseases (ESCMID)

ESCMID and ASM are jointly organising a conference to help researchers accelerate the development of new antimicrobials for drug-resistant infections...

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Theravance on Vibativ and fighting antimicrobial resistance

20 June 2016 | By Victoria White, Digital Content Producer

We recently caught up with Frank Pasqualone of Theravance Biopharma to find out about the latest study results for the company's antibiotic, Vibativ...

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Study finds amyloid-beta acts as natural antibiotic

25 May 2016 | By Victoria White, Digital Content Producer

The findings may lead to new therapeutic strategies and suggest limitations to therapies designed to eliminate amyloid plaques from Alzheimer's patient's brains...

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Soligenix on IDR technology and SGX942

10 May 2016 | By Victoria White, Digital Content Producer

We discuss Innate Defense Regulator (IDR) technology with Soligenix's Chief Scientific Officer, Dr Oreola Donini, and find out more about SGX942...

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The threat of antibiotic resistance

25 April 2016 | By Victoria White, Drug Target Review

We've created an infographic on the threat of antibiotic resistance, highlighting some of the recommendations made by the Review on Antimicrobial Resistance to date...

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Amping antimicrobial discovery with high-throughput screening

16 March 2016 | By Victoria White

Researchers from NIST have shown that high-throughput screening can dramatically speed up the challenging task of antimicrobial discovery...

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Microptosis could present an antimicrobial drug development opportunity

20 January 2016 | By Victoria White

Researchers have described a novel pathway called microptosis where the immune system's killer cells deliver a 3-phase knockout punch that kills intracellular parasites...

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Time to renew the antibiotic arsenal

19 January 2016 | By Philippe Villain-Guillot, CEO, Nosopharm

Philippe Villain-Guillot, CEO, Nosopharm, discusses antimicrobial resistance and the challenges facing antibacterial drug discovery and development...

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ESCMID publishes guidelines aimed at preventing build-up of biofilms

2 September 2015 | By Victoria White

ESCMID advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms...

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Anti-stroke drug Vinpocetine could be effective as a treatment for middle-ear infections

22 May 2015 | By Victoria White

Vinpocetine is an effective treatment for middle-ear infections, showing the ability to improve bacterial clearance and reduce hearing loss...

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Antibiotic Research UK welcomes the O’Neill Commission’s recommendation to create $2b global fund to tackle antibiotic resistance

14 May 2015 | By Victoria White

Antibiotic Research UK has welcomed this latest report to come from Jim O’Neill's Review on Antimicrobial Resistance and has endorses its recommendations...

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Biotech companies present novel approaches to fight infections at ECCMID’s pipeline corner

30 April 2015 | By Victoria White

Biotech companies presented new mechanisms and approaches in the global fight against infections in a pipeline session at ECCMID...

First patient enrolled in the New Drugs 4 Bad Bugs (ND4BB) programme

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First patient enrolled in the New Drugs 4 Bad Bugs (ND4BB) programme

3 February 2015 | By Innovative Medicines Initiative (IMI)

Two years after the start of the Innovative Medicines Initiative (IMI)-funded New Drugs 4 Bad Bugs (ND4BB) programme, the first patient has been enrolled into a Phase 2 trial sponsored by MedImmune, the global biologics research and development arm of AstraZeneca. The trial with MEDI4893 is among mechanically ventilated intubated…

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Antimicrobials