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Antiretroviral Therapies

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Combination therapy suppresses HIV-like virus in primates

8 March 2018 | By Drug Target Review

Broadly neutralising antibody treatment may target viral reservoir in monkeys...

news

Alpha-4 beta-7 protein levels linked to HIV infection risk

31 January 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...

news

MG1 virus destroys HIV-infected cells that standard therapies can’t reach

18 December 2017 | By Steve Bremer (Drug Target Review)

Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.

news

CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

gp120 protein shows promise in HIV vaccine design

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...

news

dCA accelerates HIV-1 suppression in chronically infected cells

18 October 2017 | By Dr Zara Kassam (Drug Target Review)

Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...

news

A3G protein fights HIV as monomer and dimer

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...

news

Bryostatin-1 shows early promise for dormant HIV infection

22 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have designed a synthetic molecule bryostatin-1 that can reactivate dormant HIV...

news

Three-in-one antibody may protect from HIV-like virus

20 September 2017 | By Dr Zara Kassam (Drug Target Review)

A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...

news

HIV vaccine hurdle cleared

14 September 2017 | By Dr Zara Kassam (Drug Target Review)

An international team of researchers have demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV..

news

Researchers identify a new way to treat HIV

24 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a novel variant "Delta 20" that suppresses the most damaging HIV strains...

news

Novel imaging approach offers insights into HIV’s lifecycle

21 August 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have used a novel live-cell fluorescent imaging system that has allowed them to identify individual particles associated with HIV...

news

Potential broad-spectrum antiviral discovery for herpes virus

16 August 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...

news

VRC01 antibody may prolong time to HIV viral rebound

26 July 2017 | By Dr Zara Kassam (Drug Target Review)

A study has shown the infusion of a broadly neutralising antibody (VRC01) in virally suppressed volunteers associated with a modestly delayed rebound of HIV...

news

Scientists discover how membrane necks get constricted and cut

10 July 2017 | By Niamh Marriott (Drug Target Review)

Scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have succeeded in revealing a key mechanism of membrane deformation.

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Antiretroviral Therapies