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Brochure: Diabetes Solutions
Solutions to aid understanding of cellular and molecular pathways in diabetes and translate these findings into prevention and treatment strategies.
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Assays
An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
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Case study: Parkinson’s disease modelling for drug discovery
The development of a Parkinson’s disease model, using hiPSC-derived neural cells, to assess alpha-synuclein pre-formed fibril-induced toxicity.
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Cellular Thermal Shift Assays – bringing relevant target engagement to your drug discovery workflow
11 May 2021 | By PerkinElmer
Get the Big Picture and listen to Pharma thought leaders how they view CETSA® and its impact on their Drug Discovery.
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ebook: Antibody Discovery – technology and techniques to boost development
The latest ebook from Sartorius takes an in-depth look at the technologies and techniques that have been integral to developing the antibody discovery workflow, featuring a host of expert articles, interviews and application notes.
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ebook: Antibody detection for cancer research
Gain more insight into immune-tumor interactions and learn how antibody detection techniques like multiplexing is advancing immunotherapies.
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Article: Finding a (biomarker) needle in the haystack
Summary of a neurology publication by Alnylam Pharmaceuticals: large-scale protein screening identifies novel biomarker for onset and progression of lethal ATTRv amyloidosis.
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Video: Imaging and analysis of a 3D airway organoid model
In this short video we show an example of a 3D airway organoid model along with some interesting ways to get the most out of this type of assay.
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Brochure: NEW! Upgradeable label-free biomolecular analysis
Accelerate your research with an upgradeable platform. Benefit from a fluidic-free assay format for easy and fast kinetics or analyte quantitation.
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SARS-CoV-2 infection induces polyfunctional antibodies, study finds
Using newly developed assays, researchers have characterised the antibody response of individuals infected with SARS-CoV-2.
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Assay developed to detect cathepsin B in blood samples
Scientists have created an assay to detect the protein cathepsin B in blood, a biomarker for a range of diseases.
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Hit discovery for GPCRs: HTS or virtual screens?
8 April 2021 | By Beacon Discovery
Watch our on-demand webinar and learn from an industry expert regarding GPCR virtual screening approaches and challenges and much more.
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Article: Defeating COVID-19: The science behind a new ELISA
Discover how a new ELISA against S1-RBD for COVID-19 seroconversion detection can accelerate discovery to facilitate vaccine breakthroughs.
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New in vitro assay developed to test potential NASH drugs
An assay that combines 3D disease models and automated AI-based fibrosis quantification could accelerate NASH drug discovery.
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Developing a broadly neutralising antibody therapeutic to combat SARS-CoV-2
With the ongoing COVID-19 pandemic, new treatments continue to be urgently needed. One potential solution is antibody therapeutics, which can be used to neutralise the coronavirus and provide future immunity to patients. Here, Dr Laura Walker from Adagio Therapeutics discusses how antibodies can be used in the fight against Severe…
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Application note: Effectiveness of CRISPR‑Cas9 using pools of synthetic crRNAs in high-content analysis screening experiments
In this application note, discover how pools of synthetic crRNAs can produce a phenotype as strong as, or stronger, than any one of the component crRNAs in arrayed CRISPR screening experiments.
