news
New screening hub to identify COVID-19 drugs funded in Scotland
LifeArc and the Medical Research Council have funded a new drug screening facility that will be established to accelerate COVID-19 drug discovery.
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Assays
An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
whitepaper
Whitepaper: Virus vaccine research – accelerated workflows
Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
webinar
New methods towards efficient and high-throughput drug-target screening
17 December 2020 | By Living Systems Institute, University of Exeter
Watch our on-demand webinar where we explore new methods to improve data quality from high-throughput screens. You'll learn about solutions for common problems in drug-target discovery and our keynote speaker will also look at case studies where new approaches to screening have identified high-quality candidate drugs for proliferative diseases.
news
Assay reveals potency of neutralising antibodies in COVID-19 patients
Researchers have shown that neutralising antibodies developed in COVID-19 patients were less potent if from those with severe or fatal disease.
whitepaper
Application note: One-step RT-qPCR products for high-throughput research applications
Quantitative reverse transcription PCR (RT-qPCR) involves the detection and quantification of RNA.
news
Tetracycline antibiotics show promise against Zika virus
A new study shows that methacycline, a commonly used antibiotic, can reduce the neurological damage caused by Zika virus infections in mice.
news
SARS-CoV-2 specific antibodies persist for five months in mild cases
In a study of mild-to-moderate COVID-19 patients scientists established that the level of certain antibodies remained stable for five months.
whitepaper
ebook: Phenotypic screening with iPSC-derived cardiomyocytes and neurons
Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
whitepaper
ebook: Eliminate 50/60 Hz line-frequency noise in less than one second
A major challenge within electrophysiology labs is 50 or 60 Hz line frequency electrical noise, which can either distort or completely drown out biological signal.
news
Assay to reveal anti-tumour T-cell cytotoxicity via flow cytometry developed
A simple co-culture assay that can assess anti-tumour T-cell cytotoxicity via luminescence and flow cytometry has been created.
whitepaper
Webinar: High-content analysis and phenotypic characterisation of 2D and 3D cellular models
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
whitepaper
Application note: Phenotypic characterisation of neuroactive compound effects
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.
whitepaper
Whitepaper: The impact of COVID-19 on neurological systems
Neurological symptoms have been observed in COVID-19 patients. The link between SARS-CoV-2 and the CNS is critical to developing effective treatments
video
Video: Gain deeper insights into cellular 3D structures with water immersion objectives
Water immersion objectives are essential for capturing more data at greater depths in 3D structures, such as spheroids and thick tissues.
whitepaper
Application note: Assess transduction efficiency of CFP-tagged nuclear protein with automated cellular imaging
Evaluating and quantitating nuclear transduction.
