whitepaper
Whitepaper: Addressing the challenges in biologics discovery with advanced flow cytometry
Biologics represent a growing class of drugs with indications in oncology, chronic inflammation, and autoimmune diseases.
List view / Grid view
Assays
An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
whitepaper
Application note: A kinase inhibitor phenotypic screen using a multiplex T Cell activation assay
Modulating the TCR signaling pathway using biologics, small molecules or genetic engineering is highly relevant to many therapeutic areas including cancer immunotherapy, adoptive cell therapy, vaccine development and autoimmune disease.
whitepaper
ebook: The definitive guide to understanding protein stability
Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.
webinar
Improving cell-based assays and their future in drug discovery
15 June 2020 | By Horizon Discovery
Watch our on-demand webinar with Horizon Discovery which summarises the challenges in translating promising pre-clinical therapeutic candidates into clinical success.
article
Antibody library screening: high throughput strategies
As the number of antibody discovery platforms and formats expands, various characteristics must be rigorously screened for and taken into consideration when deciding which hits to progress to successful development. The earlier in the antibody discovery pathway the assessment is carried out, the greater the hit enrichment and selection will…
video
Video: ESHG 2019 conference discussion panel: automated sample preparation
A result is only as good as the sample preparation that preceded it.
video
Video: Overview of the KingFisherTM instruments
ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.
video
Video: Isolate Circulating tumor cells using the KingFisher
New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.
whitepaper
Application note: Sensitive detection of viral nucleic acids
A simple and sensitive method for nucleic acid extraction from virus-containing samples, with a range of viral loads.
whitepaper
Application note: Metagenomic analysis of the human microbiome
Isolate high-quality, inhibitor-free DNA and RNA from human stool and other sample types suitable for metagenomics sequencing.
whitepaper
ebook: How FBDD improves hit rates & delivers high-value targets
Learn how fragment-based drug discovery improves hit rates and delivers higher-value targets using various biophysical methods.
webinar
Cell-based Surface Plasmon Resonance with AstraZeneca
4 June 2020 | By Biosensing Instrument
In this webinar, we will provide an overview of the technology with some application examples and also see a case study how AstraZeneca is exploring SPRM for studies on G-protein-coupled receptors (GPCR) in close collaboration with Biosensing Instrument.
article
The Crick HTS facility – facilitating research through large-scale screening
The high-throughput screening (HTS) facility at the Francis Crick Institute in the UK provides a core service for Crick research groups. It enables scientists to use large-scale, unbiased screening technologies and approaches as part of their research. Nikki Withers spoke to the Science Technology Platform Head, Michael Howell, to hear…
whitepaper
Guide: Five ways biophysical tools help brain studies
Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.
article
Expert view: Finding a translatable disease model suitable for drug discovery screening
Effective drug discovery and development greatly relies on the availability of predictive pre-clinical models.
