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New study helps improve the understanding of bacteria and viruses
A new study has revealed how bacterial immune systems can be harmful for their hosts and why they are not found in all bacteria.
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Bioinformatics
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Deep learning network used to model protein complexes
A new study has developed a deep learning approach that analyses protein interactions, which could improve the design of drugs in the future.
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Computational model of molecular interactions could improve new medicine development
Researchers have produced a mathematical framework enabling quick assessment of how different parameters control interactions between molecules with multiple binding sites.
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Novel pathway to target colorectal cancer identified
Researchers have found that PGE2, a signalling molecule involved in inflammation, promotes colorectal cancer progression through a microRNA and targeting that microRNA could have therapeutic potential.
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Getting connected – the key to solving the reproducibility problem?
As technology advances and scientific research progresses at a rapid pace, data is being generated in ever-larger quantities. Even with the forward strides in technology and advances in data processing, a common problem widely acknowledged by the scientific community is that of reproducibility. In this article, Matjaz Hren discusses the…
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Colon cancer proteins and gene analysis uncovers potential new treatments
A new study analysing both the entire set of genes and all the proteins produced by colon cancer tissues has revealed a more comprehensive view of the tumour.
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Simple mechanism that ensures bacterial resistance
The team used techniques used by physicists along with highly specialised equipment to investigate deep into the bacterial membrane...
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Virtual drug discovery tackles unknown universe of drugs
An online compound library consisting of the structure of over a billion molecules could be the future of drug discovery...
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‘Hidden pocket’ could be targeted to treat strokes
Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...
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Using the SVM method to predict enhancers from tissues and cell lines
A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.
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Under the microscope: CROs and microplate reader requirements
Contract Research Organisations rely on microplate readers for effective hit discovery. Ian Waddell, of Charles River Laboratories, explains what his needs are.
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Digital 3D brain cell atlas released
The Blue Brain 3D atlas could be the future of analysing all cells in the brain, with high quality, high resolution images that can navigate the brain...
whitepaper
Application note: Integrated biologics – Enabling high-throughput drug discovery at Amgen with Thermo Fisher™ Platform for Science™ Software
Every day scientists are working to discover and develop new therapies and treatments to change the lives of patients suffering from serious and debilitating illnesses. Amgen Inc. has made it a priority to unlock the potential of biology to discover, develop, manufacture, and deliver innovative therapeutics to patients.
whitepaper
Application note: Transforming your bioanalysis operations – is a lack of insight slowing you down?
Many bioanalytical labs work with a crowded and siloed set of systems and processes. From part electronic to part paper-based workflows to standalone point-solutions, the result is a lack of insight into data and slower reporting and results handling.
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scRNA-seq technique improves efficiency and accuracy of single cell RNA sequencing
Single nucleotide variations could be the key to better identification of tumour subpopulations...
