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Bioinformatics

Pushpanathan Muthuirulan Harvard University, Cambridge

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Pushpanathan Muthuirulan

13 August 2018 | By

Research Associate, Harvard University

news

Computer simulations predict the spread of HIV

2 August 2018 | By Dr Zara Kassam (Drug Target Review)

Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...

news

Is acidity the weakness of cancer cells?

1 August 2018 | By Drug Target Review

Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...

news

Novel antibiotics can be found on common weeds

31 July 2018 | By Drug Target Review

The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...

news

New ligand binding site identified through computer simulations

30 July 2018 | By Drug Target Review

Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...

news

Recessive disorder impairing eyesight has been discovered

24 July 2018 | By Drug Target Review

Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...

news

Tau mutations may increase cancer risk

25 May 2018 | By Dr Zara Kassam (Drug Target Review)

Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...

article

Computational methods for drug repositioning

17 February 2016 | By Anaum Rashid (University of Sunderland), Hannah Smith (University of Sunderland), Ken McGarry (University of Sunderland)

Bioinformatics and computational techniques are now experiencing increased attention as a means of improving the costly and time-consuming drug development process...

article

Should LC-MS/MS proteomics guide targeted drug selection for cancer patients?

22 September 2015 | By David Britton (Barts Cancer Institute), Pedro Cutillas (Barts Cancer Institute)

History has demonstrated that the use of companion in vitro diagnostic tests to select cancer patients positive for a drug target significantly improves response to targeted anti-cancer therapies...

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