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Bioinformatics

news

Recessive disorder impairing eyesight has been discovered

24 July 2018 | By Drug Target Review

Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...

news

Tau mutations may increase cancer risk

25 May 2018 | By Dr Zara Kassam (Drug Target Review)

Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...

article

Computational methods for drug repositioning

17 February 2016 | By Anaum Rashid (University of Sunderland), Hannah Smith (University of Sunderland), Ken McGarry (University of Sunderland)

Bioinformatics and computational techniques are now experiencing increased attention as a means of improving the costly and time-consuming drug development process...

article

Should LC-MS/MS proteomics guide targeted drug selection for cancer patients?

22 September 2015 | By David Britton (Barts Cancer Institute), Pedro Cutillas (Barts Cancer Institute)

History has demonstrated that the use of companion in vitro diagnostic tests to select cancer patients positive for a drug target significantly improves response to targeted anti-cancer therapies...

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