news
Computer simulations predict the spread of HIV
Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...
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Bioinformatics
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Is acidity the weakness of cancer cells?
Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...
news
Novel antibiotics can be found on common weeds
The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...
news
New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
news
Recessive disorder impairing eyesight has been discovered
Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...
news
Tau mutations may increase cancer risk
Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...
article
Computational methods for drug repositioning
Bioinformatics and computational techniques are now experiencing increased attention as a means of improving the costly and time-consuming drug development process...
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Should LC-MS/MS proteomics guide targeted drug selection for cancer patients?
History has demonstrated that the use of companion in vitro diagnostic tests to select cancer patients positive for a drug target significantly improves response to targeted anti-cancer therapies...