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ebook: Vaccines in the digital age
In this ebook, we’ll see how digitally enabling your organisation can increase capacity and improve vaccine production.
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
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Whitepaper: Automated cell culture and screening
This whitepaper describes the automated culturing of hiPSC-derived cells for high-throughput phenotypic screening, using validated phenotypic assays.
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Could bile acids play a role in Parkinson’s pathogenesis?
A new study suggests bile acids may act as a valuable biomarker for diagnosing and tracking the progression of Parkinson's disease.
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Biomarkers predict Alzheimer’s five years before onset
The discovery of early plasma biomarkers for Alzheimer's disease could transform outcomes by enabling patients to begin treatment early.
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Whitepaper: Why BioPharma Lifecycle Management?
In this whitepaper we explore some of the major bottlenecks in the development lifecycle and the current barriers to effective digital transformation.
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Biomarker in blood could determine severity of COVID-19
A study has shown that patients with severe COVID-19 have significantly elevated levels of M-MDSCs in their blood compared with healthy individuals.
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Application note: Automated Simple Westerns in targeted protein degradation
Learn how Simple Western automated immunoassays screen degraders and IMiD compounds to quantify degradation activity, providing accurate DC50 and Dmax values.
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Application note: Evaluation of different ion-pairing reagents for LC/UV and LC/MS analysis of oligonucleotides
The effect of various ion pairing reagents (amines and acidic counterions) on the LC/UV and LC/MS analysis of oligonucleotides (ONs) has been studied.
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ebook: The organoid culture handbook
This tissue-specific handbook brings you key publications, in-house protocols and troubleshooting recommendations for your organoid cell culture.
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Whitepaper: Virus vaccine research – accelerated workflows
Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
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Biomarkers for predicting COVID-19 disease severity
Scientists have created a prognostic classification model which uses biomarkers to help predict an individual’s risk of developing severe COVID-19 symptoms.
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Biomarker for blood vessel damage found in children with SARS-CoV-2
Elevated levels of a biomarker related to blood vessel damage have been found in all children with SARS-CoV-2 infection.
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Mitochondrial protein revealed as target for cardiovascular disease
According to new research, the protein ALDH4A1 is a possible therapeutic target and diagnostic biomarker for cardiovascular disease.
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Precision medicine beyond oncology
The field of oncology has successfully applied precision medicine approaches to diagnosis and treatment. Success has been driven by a growing understanding of the underlying biology of cancer; the emergence of innovative tools and technologies for biomarker identification and detection; and considerable advocacy by patients, physicians and policymakers that has…
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Endosomal trafficking could be a target for Alzheimer’s therapies
Researchers have shown that 70 percent of Alzheimer’s patients have high levels of proteins associated with dysfunction in the endosomal trafficking system in their spinal fluid.