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Biomarkers to detect and prevent liver cancer
An increase in the expression of sugar-burning 'glycolytic' enzymes in precancerous cirrhotic livers has been identified and could be used as a biomarker...
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
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Droplet Digital PCR detects and quantifies cancer mutation
Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...
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Water as a biomarker against cancer?
The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...
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CRISPR technique identifies Alzheimer’s biomarker
UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...
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CT45 biomarker found in ovarian cancer can predict response to therapy
New approach could prolong survival and trigger an immune...
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Metabolomics in drug and biomarker discovery
Metabolomics is the state-of-the-art qualitative or quantitative analysis of metabolites present in biological samples. Since the majority of diseases are associated with metabolic alterations – either as a cause or result of the disease process – metabolomics is increasingly being used in drug and biomarker discovery.
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New biomarker panel could accelerate autism diagnoses
Researchers have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD)...
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Expert view: Generate high‑content information using flow cytometry
Flow cytometry has become a widely used technology in life science research since its development in the 1970s. It is also essential for many biopharmaceutical and biotechnology companies due to its proficiency in identifying biomarkers, finding new inhibitory antibodies, and assessing the efficiency of new pharmacological protocols.
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New blood test to screen for secondary heart attack
A blood test that quickly and easily detects whether a person is at risk of a secondary heart attack is being developed by scientists at the Baker Heart and Diabetes Institute...
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Novel imaging biomarker to help predict coronary inflammation
Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality...
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Brain-heart link points at potential biomarker for trauma-induced epilepsy
Scientists at Penn State find that heartbeat irregularities connected to brain activity abnormalities may pave the way to predict onset of epilepsy in certain patients…
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Potential indicator for the early detection of dementias
A team of neuropathologists worked together to show that the impairments affecting mitochondria also affect neighbouring organelles...
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Breath tests could detect pancreatic cancer
Breath tests analysing organic compounds in exhaled breath could be used as a new diagnostic tool for pancreatic cancer...
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HRI depletion may be effective in treating sickle cell disease
A protein identified in the signalling pathway for haemoglobin production has been identified as a possible target to treat sickle cell disease (SCD)...
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SPECT Imaging technique illuminates immune status of monkeys with HIV-like virus
Approach could improve understanding of immune system recovery in people treated for HIV infection...