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Biomarkers may help provide personalised treatment for brain cancer
Researchers in Brazil have identified seven biomarkers that could be used to indicate which glioma patients are likely to experience an aggressive form of the brain cancer.
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
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Fragile X imaging study reveals differences in infant brains
For the first time, researchers have used MRIs to show that babies with the neurodevelopmental condition fragile X syndrome had less-developed white matter compared to infants that did not develop the condition...
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Alzheimer’s patients exhibit changes in certain blood lipids typical of premature ageing
Research at MedUni Vienna’s Centre for Brain Research has investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer’s disease.
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Tracking changes in circulating tumour cells shows promise for cancer screening
Researchers in the United States have developed improved methods for capturing circulating tumour cells (CTCs) on clinical samples, with a view to assessing treatment for cancer patients and screening for the disease.
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Streamlining drug discovery assays for cancer and cardiovascular disease
Declining R&D productivity is a key challenge in the pharmaceutical industry. To increase the success rate of candidate drugs entering the clinical phase, companies must address the early stages of drug discovery.
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Nanopore sensors used to detect molecular biomarkers for osteoarthritis
Scientists have been able to measure a specific molecule indicative of osteoarthritis and a number of other inflammatory diseases using a newly developed technology...
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Scientists discover critical molecular biomarkers of preeclampsia
Small non-coding RNAs may be used to devise a diagnostic blood test for pregnant women...
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Immune signature predicts asthma susceptibility
Researchers have identified a subset of T cells, whose frequency serves as early childhood immune signature that predicts the risk of developing asthma later on.
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Novel classification can lead to new ways to diagnose and treat cancer
A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.
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Genomic sequencing augments diagnosis and treatment of lymphoid cancer
New assay may allow screening for 'actionable' gene mutations in routinely acquired archival biopsies...
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Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer
A new study has established that hybrid-capture sequencing is the method of choice for sequencing “actionable” gene mutations across the most common forms of lymphoid cancer.
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Study indicates holistic nature of Alzheimer’s disease (AD) progression
A collaboration of scientists in the United States has identified a distinct association between inflammation biomarkers in blood plasma and cerebrospinal fluid (CSF), and markers of Alzheimer’s disease (AD).
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Study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...