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Biomarkers

 

Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.

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Strategies for identifying predictive biomarkers of non-alcoholic fatty liver disease

17 March 2016 | By , , ,

Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life styles and high fat diets, has an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within genes such as PNPLA3, TM6SF2, APOC3, NCAN and PPP1R3B correlate…

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New biomarkers may influence cancer drug design

22 January 2016 | By Victoria White

The research from Georgia State University scientists provides strong translational potential with respect to biomarkers that play critical roles in the development of endometrial/lung tumours...

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Drug Target Review – Issue #4 2015

3 December 2015 | By Drug Target Review

Included in this issue: Biomarkers, Mass Spectrometry, Target Validation, Drug Development, Personalised Medicines, Next-Generation Sequencing, Protein Expression, Companion Diagnostics, and much more...

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Biomarkers as molecular footprints for cancer therapy: current perspectives and promises

3 December 2015 | By , , ,

Knowledge about cancer biomarkers has increased tremendously and provides clinicians and researchers with valued opportunities to understand the molecular mechanism of cancer, thus applying it to effective, early-stage diagnosis and treatment. Cancer biomarkers include a vast range of biochemical molecules such as nucleic acids, proteins, sugars, lipids, small metabolites, cytogenetic…