news
Unidentified proteins provide new way to diagnose ovarian cancer
Japanese study has identified three previously unknown membrane proteins in ovarian cancer, using a new detection method consisting of nanotechnology and imaging techniques.
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
news
New biomarker identified for major depressive disorder
Local gyrification index, which measures cortical folding in the brain, could be a novel neuroimaging marker for major depressive disorder.
whitepaper
Application note: Novel screening tools for TMEM175 drug discovery
In this article, learn about how TMEM175 is an exciting new target in normal physiology and in disease. Also, read about how the use of biomarkers in Alzheimer’s drug development will address many of the challenges currently encountered.
whitepaper
Application note: How to improve glycoform and glycopeptide coverage for mucin preparations
Here we explore using a mucin-selective protease for tryptic-digest sample preparation of two mucin proteins and assess its potential to improve detecting glycoforms and glycopeptides.
webinar
Cardiac and vascular safety liabilities using totality of evidence approach
27 June 2023 | By Eurofins Discovery
US-FDA recommend integration of both preclinical (S7B) and clinical (E14) data to improve risk assessment, reduce reliance on TQT clinical studies, streamlined drug-development, simplified decision-making processes, effective risk-communication.
news
Predicting cerebrovascular diseases with retinal imaging
New imaging approach reveals that changes in retinal microcirculation may indicate cerebrovascular diseases that involve reduced blood flow.
webinar
Innovations in organoid modelling for disease modelling and cell therapy
14 June 2023 | By Sartorius
Watch our virtual panel, where you'll uncover the game-changing advantages of organoids over traditional 2D cultures. Our experts will explore the immense potential of organoids in oncology and immuno-oncology research.
webinar
Normalization of organ-on-a-chip samples for mass spectrometry based proteomics and metabolomics via dansylation-based assay
19 May 2023 | By CN Bio
A discussion of the recently published paper, “Normalization of Organ-on-a-Chip Samples for Mass Spectrometry Based Proteomics and Metabolomics via Dansylation-based Assay,” and how the field can produce more replicable experiments.
news
Study links nutrients, brain structure, cognition in healthy aging
US researchers found that nutrient intake, brain structure and cognitive function contribute to healthier brains in aging adults, by looking at correlating blood markers.
news
Biomarkers show promise for identifying early risk of pancreatic cancer
The finding is an critical first step towards classifying lesions on the pancreas that are at highest risk of becoming cancerous, enabling their removal before they start to spread.
whitepaper
Whitepaper: PSMA Protein in the Battle Against Cancer
The PSMA Protein is a new therapeutic hot target. In this article, learn about its growing role in the fight against prostate cancer and beyond.
video
Video: Spatial imaging as a tool for discovery
Watch Dr David Rimm from the Yale School of Medicine talk about his recent work and take on the future of multiplex spatial profiling of the TME.
whitepaper
Application note: Developing next-gen in vitro Huntington’s disease assays
The use of high-density MEAs to probe single cell and network activity electrophysiology of a hiPSC-derived Huntington’s disease model
whitepaper
Whitepaper: Cell cycle and DNA damage and repair
Explore pathways of cell cycle control, revealing mechanisms of cell cycle arrest, DNA damage and senescence using this ebook.
news
Unexpected neuronal molecule makes prostate cancer more aggressive
US researchers discover a potential therapeutic avenue through the molecule NgR2, against an aggressive form of prostate cancer.
