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Poster: Assays for DDX3, DDX5, DDX17, RIG-I, and MDA5
A panel of HTS assays was developed using the Transcreener platform to accelerate the development of selective helicase inhibitors.
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Biopharmaceuticals
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Poster: Assays for PRMT5, MLL4, METTL3/14, & NSP14
AptaFluor SAH: A Homogenous, Universal Assay for Histone, RNA, & DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, & NSP14
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A Guide to Measuring Drug-Target Residence Times
This guide provides technical background on concepts and techniques for use of Transcreener biochemical assays to measure drug-target residence times.
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Whitepaper: Targeting kinases in the innate immune response
The guide provides examples of how Transcreener allowed rapid assay development to enable screening for kinases in innate immune pathways.
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Case Study: Target discovery for rheumatoid arthritis
Learn more about Euretos computational disease model and how it predicts many of the known drug targets for RA.
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A Guide to DNA Damage Response and Innate Immunity
In this guide, we provide an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets.
webinar
Advancing therapeutics targeting cytokines with functional cell-based assays
3 January 2024 | By Eurofins DiscoverX
Watch this webinar to discover functional cell-based assays for characterizing novel therapeutics & biosimilars targeting cytokines in inflammation & oncology.
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Application note: Solutions for your protein sample preparation workflow challenges
Researchers often encounter common problems during protein sample preparation which can compromise the quality and quantity of protein obtained. Explore our solutions to these common challenges, including sample handling, storage and preparation method issues.
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eBook: Advancing 3D Culture Imaging For Biopharma
Download this FREE eBook, which explores some of the challenges encountered when imaging 3D culture models such as organoids and spheroids, and sheds light on innovative microscopy solutions that can empower scientists to make new advances in areas such as regenerative medicine, drug discovery, and disease research.
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ebook: Maximizing preclinical confidence in target efficacy and safety
This ebook outlines Euretos’ approach to target discovery and indication expansion. Whilst also discussing data-driven target selection.
podcasts
Episode 20- Regulations on artificial intelligence- impact on drug discovery
Tune in to this episode to hear experts discussing the hot topic that is AI and how AI technology is used in drug discovery, looking specifically at how Biotechs & Pharma are trying to keep up with emerging technology.
webinar
Bridging the gap: using organ-on-a-chip as an experimental tool to develop (cost) effective therapeutics
25 July 2023 | By CN Bio
The webinar will explore primary concerns in drug discovery development and why drugs fail.
webinar
Functional assays for the development of agonistic antibodies
20 July 2023 | By Eurofins DiscoverX
Watch this webinar to discover qualified bioassays assessing therapeutic antibody mechanisms, case studies about agonistic effects in antibodies initially deemed antagonistic, and explore Fc receptor impacts on antibody response in co-culture assays.
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Case study: Mitochondrial toxicity in drug discovery and development
The Agilent Seahorse XF assay platform has opened new avenues for examining mitochondrial health in a timely and effective manner.
webinar
Innovations in organoid modelling for disease modelling and cell therapy
14 June 2023 | By Sartorius
Watch our virtual panel, where you'll uncover the game-changing advantages of organoids over traditional 2D cultures. Our experts will explore the immense potential of organoids in oncology and immuno-oncology research.