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Cancer research

The potential of CD24 in cancer immunotherapy

27 December 2023 | By Dr Roy Maute (Pheast Therapeutics)

Cofounder & Chief Scientific Officer of Pheast Therapeutics, Dr Roy Maute, reveals his company’s promising drug candidate and explains why they have focused on their chosen target.

DNA helix colorful genes chromosomes DNA sequence, DNA structure with glow. Science concept background 3d rendering

news

How gene regulatory networks maintain FLT3-ITD mutated AML

22 December 2023 | By Drug Target Review

Using shRNA screening enabled researchers to investigate the roles of individual specific factors in maintaining the network found in AML.

article

Drug Target Review Immuno-oncology eBook 2023

22 December 2023 | By

Download this eBook for FREE. Explore cutting-edge immuno-oncology insights through exclusive interviews and studies by leading experts in the field.

news

New insights about the development of hematopoietic stem cells

21 December 2023 | By Drug Target Review

Understanding the involvement of Nod1 in the development of blood stem cells could greatly improve blood disorder treatments.

article

New understanding of the TMEJ pathway in cancer

14 December 2023 | By Ellen Capon (Drug Target Review)

Cancer treatment may be majorly impacted by new findings about the polymerase theta-mediated end joining time DNA repair pathway.

MRI of a glioblastoma in the brain of a patient (in frontal lobe near the right eye)

news

Perivascular fibroblasts support glioblastoma tumours

13 December 2023 | By Drug Target Review

Glioblastomas can resist immunotherapy as perivascular fibroblasts support the creation of an immunosuppressive tumour environment.

news

New organoid model of neuroendocrine tumours developed

13 December 2023 | By Drug Target Review

NETs require epidermal growth factor to grow, meaning that inhibiting EGF receptors could treat these types of tumours.

whitepaper

eBook: A Microscopy Guide For Spatial Biology

11 December 2023 | By Leica Microsystems

In this eBook, discover how to better understand tissue landscapes with different microscopy techniques including multiplex imaging.

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Investigating the genetic changes of the DDX3X gene

8 December 2023 | By Drug Target Review

Using saturation genome editing, researchers have created a map of disease-causing mutations for neurodevelopmental disorders and cancer.

article

New gene found plays essential role in stem cell differentiation

8 December 2023 | By Ellen Capon (Drug Target Review)

Intestinal organoids allowed researchers to understand how Rnf43 and Daam1 influence the balance of stem cell renewal and differentiation.

news

Gene therapy reduces hepatocellular carcinoma in mice

8 December 2023 | By Drug Target Review

Increasing microRNA-22 overexpression in a gene therapy approach treated HCC in mice, offering promise for its prevention and treatment.

whitepaper

Beyond the lab: cancer research

6 December 2023 | By Drug Target Review

Our inaugural report is an exploration of the remarkable advancements in cancer research and the field of drug discovery.

Scientists can now 'listen in' on cancer cells with new technique

news

Novel computational model to study cancer dynamics

1 December 2023 | By Drug Target Review

An advanced computational model enables scientists to study how cancer cells navigate through blood vessels.

news

Discovery of molecular pathway could target lung cancer

1 December 2023 | By Drug Target Review

New findings about how RBM10 inhibits lung cancer growth offers potential for an anti-cancer drug and more personalised treatment.

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New AI model can evaluate invasive breast cancer outcomes

28 November 2023 | By Drug Target Review

Combining cancerous and non-cancerous cell patterns, the AI model evaluates breast cancer outcomes better than expert pathologists.

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Cancer research