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Cancer research

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DNA epigenetic changes: a key cause of cancer

7 November 2023 | By Drug Target Review

Analysis of cells shows many regions in DNA are differentially activated or inactivated in a cancer-specific manner.

news

Protein found to control breast cancer metastasis

30 October 2023 | By Drug Target Review

Scientists have discovered the motor protein dynein commands movement of cancer cells in soft tissue models, offering new clinical targets.

news

Role of enzyme in tumour immune microenvironment identified

26 October 2023 | By Drug Target Review

Researchers have found that reducing glycosylation on the T cell surface may offer new approaches to cancer immunotherapy.

news

New molecule disrupts pathways that promote cancer growth

26 October 2023 | By Drug Target Review

Researchers have discovered a molecule that binds to a cancer cell protein, stopping growth of breast and ovarian tumours.

news

Key epitope can trigger tumour cell death

24 October 2023 | By Drug Target Review

An epitope on CD95 receptor causes tumour cells to self-destruct and may prolong benefits of CAR T-cell therapy for solid tumours.

Glioblastoma brain cancer cells under microscope

news

mRNA reverses the glioblastoma immunosuppressive environment

23 October 2023 | By Drug Target Review

Extracellular vesicles loaded with mRNA encoding interferon-gamma offers promise for treating difficult tumours.

news

Cancer-killing T cells enhanced by engineered bacteria

20 October 2023 | By Drug Target Review

Bacteria programmed to paint targets on solid tumours for T cells to see eliminates the need for specific antigens.

article

Novel method for early cancer diagnosis

18 October 2023 | By Taylor Mixides (Drug Target Review)

A recent scientific collaboration, led by the Institute of Nuclear Physics of the Polish Academy of Sciences, has overcome measurement challenges, enabling reliable cancer diagnosis.

news

Midbody remnants following mitosis could combat cancer

13 October 2023 | By Drug Target Review

Midbody’s role in cell signalling and stimulating cell proliferation offers an opportunity to detect cancer.

news

Pancreatic tumours fooled by glutamine mimic

13 October 2023 | By Drug Target Review

A novel treatment approach using DON molecule starves tumours of essential nutrient, significantly slowing tumour growth.

multiple DNA strands with gene regions highlighted in green

news

Gene expression signatures improve prognostic ability

11 October 2023 | By Drug Target Review

Thousands of breast cancer gene expression signatures analysed.

news

Nutrient programmes immune cells to battle infection and cancer

10 October 2023 | By Drug Target Review

Research suggests immune and non-immune cells can be reprogrammed by changing how nutrients are used.

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Cancer research