news Hymecromone can suppress neuroinflammation in astrocytes, study shows 1 March 2021 | By Victoria Rees (Drug Target Review) Researchers have found that the spasmolytic drug hymecromone can suppress astrocyte inflammatory responses, meaning it could be used to combat Alzheimer's disease.
news Computational method used to quantify tRNAs in any organism 1 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a new technique called mim-tRNAseq to measure, map and analyse tRNAs in cells, providing insight into disease.
whitepaper ebook: Revolutionise your lab with a cutting-edge bioprocess platform to drive quality and efficiency 26 February 2021 | By IDBS With the right solution organisations can simplify their lab-based working, while ensuring the highest level of compliance with regulatory requirements.
news New technology enables predictive design of engineered human cells 22 February 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a computer modelling programme that can produce genetic circuits for cellular engineering.
news Bile duct organoids could be used as cell therapy for regenerative medicine 19 February 2021 | By Victoria Rees (Drug Target Review) For the first time, scientists have grown bile duct organoids that could repair damaged ducts and livers as a new cell therapy.
news NAD depletion by IFN sensitises pancreatic cancer to NAMPT inhibition, study shows 19 February 2021 | By Victoria Rees (Drug Target Review) High IFN signalling in pancreatic tumours are sensitive to NAMPT inhibitors which block a pathway in NAD synthesis, presenting a drug target.
news D614G Spike mutation makes SARS-CoV-2 up to eight times more infectious 18 February 2021 | By Victoria Rees (Drug Target Review) A study has shown the D614G mutation in the Spike protein of SARS-CoV-2 makes the coronavirus more transmissible than the original virus from China.
news New drug combination could combat Diffuse Intrinsic Pontine Glioma 17 February 2021 | By Victoria Rees (Drug Target Review) The drug combination of difluoromethylornithine and AMXT 1501 has shown success against Diffuse Intrinsic Pontine Glioma in animal models.
whitepaper ebook: Vaccines in the digital age 11 February 2021 | By IDBS In this ebook, we’ll see how digitally enabling your organisation can increase capacity and improve vaccine production.
news CRISPR used to model acute myeloid leukaemia progression 11 February 2021 | By Victoria Rees (Drug Target Review) CRISPR-Cas9 and stem cell technologies have been used to create a cellular model of acute myeloid leukaemia, revealing therapeutic targets.
whitepaper Whitepaper: Automated cell culture and screening 8 February 2021 | By Ncardia This whitepaper describes the automated culturing of hiPSC-derived cells for high-throughput phenotypic screening, using validated phenotypic assays.
news Novel enterocyte-like cells developed by researchers from stem cells 8 February 2021 | By Victoria Rees (Drug Target Review) A team has developed enterocyte-like cells from hiPSCs, which can be used to study the absorption of novel oral drugs.
news Flaw found in lab models used to study human blood-brain barrier 8 February 2021 | By Victoria Rees (Drug Target Review) Researchers have uncovered a flaw in lab models used to study the human blood-brain barrier and a potential strategy to correct the error.
news Researchers identify how Zika infects foetuses and a potential drug to prevent it 4 February 2021 | By Hannah Balfour (Drug Target Review) According to scientists, maternal cells act as a reservoir for Zika, enabling the virus to pass from mother to foetus during pregnancy.
whitepaper Whitepaper: Why BioPharma Lifecycle Management? 28 January 2021 | By IDBS In this whitepaper we explore some of the major bottlenecks in the development lifecycle and the current barriers to effective digital transformation.
