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‘Tricking’ bacteria could lead to more effective antibiotics
A technique to 'trick' bacteria into revealing pores in their cell walls has been developed and targeting these could make antibiotics more effective.
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Cell Cultures
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3D tissue models of brain tumours created in brain-mimicking environment
A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
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New compound keeps cells alive and functioning in a healthy state
A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.
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Anticancer activity delivered by targeting mitochondrial cell regulator
Disruption of the MFF-VDAC1 complex could lead to a potential therapeutic target for cancer.
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Weapon bacteria could be copied to create new forms of antibiotics
New antibiotics could be designed by discovering the mechanism a weapon bacteria uses to vanquish their competitors.
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New technology developed to screen for Huntington’s treatments
Researchers have created a new technology which enabled them to discover more about the causes of Huntington’s disease and which can be used to test drugs.
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Recent trends in upstream bioprocessing and major challenges in process development
Aparajita Dubey summarises the recent trends in upstream bioprocessing and highlights the challenges and solutions involved in its process development.
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Spotlighting data in upstream bioprocesses – a recipe for quick and successful cell lines
Upstream bioprocessing is the epicentre of biologics development, wherein scientists piece together a series of carefully chosen processes with contributing components and parameters to enable the production of highly effective biotherapeutics. Unjulie Bhanot explains why an effective data management system is vital in this quest for the next big therapeutic.
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Transplanted brain stem cells survive without anti-rejection drugs in mice
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
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Nervous system discovery overturns previous theory
A ground-breaking nervous system discovery could be significant for the treatment of different neurological diseases.
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Expert view: Clarification of cell cultures without centrifugation
Monoclonal antibodies are used in a wide range of applications, such as basic research, biopharmaceutical development and in vitro diagnostics.
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Upstream Bioprocessing In-Depth Focus 2019
This In-Depth Focus features articles highlighting the importance of effective data management strategies as well as the recent trends in upstream bioprocessing.
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Compound promotes healing of myelin in nervous system disorders
A compound that promotes the rebuilding of the protective sheath around nerve cells damaged in multiple sclerosis has been developed.
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Scientists identify promising new target to combat Alzheimer’s disease
New research is the first to link maladaptive changes in calcium transport by mitochondria to the progression of Alzheimer's disease.
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Pancreas-on-a-chip technology to aid in diabetes research
Scientists combine organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research.