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Scientists identify promising new target to combat Alzheimer’s disease
New research is the first to link maladaptive changes in calcium transport by mitochondria to the progression of Alzheimer's disease.
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Cell Cultures
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Pancreas-on-a-chip technology to aid in diabetes research
Scientists combine organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research.
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How bacteria behind hospital infections block out antibiotics revealed
Scientists have shown that drug-resistant bacteria infections shut out antibiotics by closing tiny doors in their cell walls.
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Breast cancer ‘sleeper cells’ could be formed after drug treatment
Breast cancer medicines may force some cancer cells into 'sleeper mode', allowing them to potentially come back to life after treatment.
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Stem cell division in the geriatric brain blocked by signal
It has been discovered that Id4 controls whether stem cells enter cell division and may be relevant for treating neurodegenerative disease.
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Telomere damage in cells is caused by runaway mitochondria
Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
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Application note: Monitor cell proliferation and cell cycle in real time
There is an increasing need to expand the variety and complexity of cell-based assays for biological research and drug discovery.
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Flyer: Affinity Column for Fast Evaluation of ADCC Activity
TSKgel FcR-IIIA-NPR is based on a recombinant FcγIIIa receptor ligand immobilized on a non-porous polymer particle. It allows fast assessment of biologic activity of monoclonal antibodies.
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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Single enzyme provides target for new sepsis drugs
Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
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Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
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OX40-expressing follicular helper T cells can control rheumatoid arthritis
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
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Newly discovered signal could lead to anti-cancer therapies
Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.
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Transfer of oncogene in colon cancer cells demonstrated
A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
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Whitepaper: IHC/ICC Protocol Guide
Immunohistochemistry (IHC) and immunocytochemistry (ICC) are techniques employed to localize antigen expression and are dependent on specific epitope-antibody interactions.