news Single enzyme provides target for new sepsis drugs 14 August 2019 | By Rachael Harper (Drug Target Review) Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
news Protective protein guards against DNA damage 5 August 2019 | By Rachael Harper (Drug Target Review) It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
news OX40-expressing follicular helper T cells can control rheumatoid arthritis 1 August 2019 | By Rachael Harper (Drug Target Review) New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
news Newly discovered signal could lead to anti-cancer therapies 31 July 2019 | By Drug Target Review Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.
news Transfer of oncogene in colon cancer cells demonstrated 22 July 2019 | By Drug Target Review A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
whitepaper Whitepaper: IHC/ICC Protocol Guide 22 July 2019 | By Bio-Techne Immunohistochemistry (IHC) and immunocytochemistry (ICC) are techniques employed to localize antigen expression and are dependent on specific epitope-antibody interactions.
whitepaper Whitepaper: Neural Cell Culturing Guide 22 July 2019 | By Bio-Techne The advent of in vitro culturing of neural cells has been central to driving our understanding of the nervous system.
news Omega-6 fatty acid could help fight heart disease 19 July 2019 | By Drug Target Review Scientists have shown that an omega-6 polyunsaturated fatty acid could halt the progression of atherosclerosis, a leading cause of heart disease.
news New evidence shows cytotoxic T cells can destroy targets of large mass 10 July 2019 | By Drug Target Review New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
news Secondary structures study could lead to making cancer cells vulnerable 9 July 2019 | By Drug Target Review Researchers have used machine learning to discover that the two most widespread DNA structures cause genome mutations that lead to cancer.
news New discovery shows ability of Schwann cells to generate myelin 8 July 2019 | By Drug Target Review Research from Oregon Health & Science University could lead to new therapies to heal nervous system disorders.
news Stem cell stimulation shown to improve stroke recovery 2 July 2019 | By Drug Target Review Stem cell stimulation shows promise as a potential noninvasive stroke treatment.
news Light-stimulated brain cells could aid in stroke recovery research 1 July 2019 | By Drug Target Review A new 'optochemogenetics' research approach from scientists at the Emory University School of Medicine could aid in helping stroke victims.
news Protective antibodies identified that could be key to malaria vaccine 18 June 2019 | By Drug Target Review A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.
news First blood-brain barrier chip using stem cells developed 13 June 2019 | By Drug Target Review Researchers have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells.