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New approach shows regeneration of severely damaged lungs
Researchers are first to demonstrate in a clinically relevant model that damaged lungs can be regenerated to meet transplantation criteria.
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Cell Regeneration
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Scientists restore functions in pig’s brain hours after death
Scientists have reported circulation and cellular activity being restored in a pig's brain four hours after its death, challenging long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death.
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Nuclear tracers help assess new drugs for neurodegenerative diseases
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
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Application note: GABAA Receptors
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
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Compounds in coffee may fight Parkinson’s
Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration...
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Stimulating fibroblasts can trigger hair growth in wound healing
Stimulating fibroblasts through the sonic hedgehog pathway can trigger hair growth not previously seen in wound healing...
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MRI scans shows promise in predicting dementia
Brain changes evident in scans before memory, cognitive decline...
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Powerful molecules provide new findings about Huntington’s disease
Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...
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Scientists uncover the role of PRMT5 in the production of myelin-forming cells
The discovery is a major step toward understanding the mechanisms of myelin production and the potential for treating certain central nervous system diseases...
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Alpha-synuclein clumps promote Parkinson’s progression
Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...
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EMT activation in tissue growth is also at play in cancer metastasis
Scientists in the USA have added a new dimension to the understanding of how cells alter their communication with one another by means of epithelial mesenchymal transition (EMT) during development, wound healing, and the spread of cancer.
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Stem Cells In-Depth Focus 2018
In this issue: urine-derived stem cells offer an innovative platform for drug testing and disease modelling, a paradigm shift in translational stem cell research, and the role of biomaterials in stem cell-based regenerative medicine.
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Microglia in the retina can spontaneously regenerate
NIH discovery in mice could lead to therapies to reduce vision loss from diseases of the retina...
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Scientists identify new stem cell that helps regenerate lung tissue after trauma
Researchers from the University of Pennsylvania have identified a lung stem cell that repairs the organ's gas exchange compartment, providing potential new approach to treat lung disease.
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Heart-muscle patches improve heart attack recovery
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals the patches significantly improved recovery from heart attack injury...