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New drug Metavert blocks growth of pancreatic cancer in mice
Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.
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Chemotherapy
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Researchers successfully use AI to facilitate dynamic dosing for metastatic cancer
Scientists have harnessed a powerful artificial intelligence (AI) platform, CURATE.AI, to successfully treat a patient with advanced cancer by completely halting disease progression, representing a big step forward in personalised medicine.
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GC4419 could prevent debilitating side effect of cancer treatment
Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
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CBD improves survival rates of mice with pancreatic cancer
Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...
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Cancer drug screening: the historical perspective
Chemotherapy with cytotoxic and growth inhibitory drugs have played an important role in cancer therapy, used either alone or in combination with other treatment modalities such as surgery, radiation or biological therapy. Chemotherapy, in most instances, was the only alternative treatment for metastatic cancer – mainly given as drug combinations...
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Screening In-Depth Focus 2018
This In-Depth Focus reviews the history of cancer treatments, looks at improving the translation of disease biology though phenomics, and considers how to enhance cell bioprocessing through cell-based combinatorial culture.
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Scientists mine gene responses to existing chemotherapies to facilitate precision cancer treatment
Scientists utilise computational biology techniques in a bid to enable doctors to use targeted therapies for cancer patients.
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Man-made antibodies show promise in attacking cancer cells in animal models
Molecules called aptamers could form new, safer chemotherapy delivery systems...
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SLU scientist turns off chemo pain in the laboratory
Saint Louis University researchers have had success in an animal model in turning off the excruciating pain that often accompanies a colorectal cancer drug.
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
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Kenpaullone protects from cisplatin-induced hearing loss
Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...
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Blocking 20-HETE chemical counters the siren call of aggressive cancers
Scientists have successfully blocked the powerful call of two types of aggressive cancer – glioblastoma and breast cancer – in laboratory models; with evidence that inhibiting the chemical 20-HETE halts tumour growth.
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Drug may curb female infertility from cancer treatments
An existing drug may protect premenopausal women from life-altering infertility that commonly follows cancer treatments...
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First ‘haploid’ human stem cells could change the face of medical research
Research has yielded the first successful isolation and maintenance of haploid embryonic stem cells in humans.
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New cancer drug tested in mice may benefit certain leukaemia patients
Almost 6,000 new cases of acute lymphoblastic leukaemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.