Clinical Trials

Cancer vaccine shows promise for HER2-positive cancers

1 October 2018 | By Drug Target Review

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers...

Kidney disease biomarker could help detect COPD

28 September 2018 | By Iqra Farooq (Drug Target Review)

A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...

Agilent Technologies

Amyloid beta – a good therapeutic target?

19 September 2018 | By Iqra Farooq (Drug Target Review)

Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...

Carving a pathway toward personalised cancer therapy

11 September 2018 | By Drug Target Review

Individualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, treatment and care. However, several challenges remain before these approaches can be widely used in the clinic.

CBD improves survival rates of mice with pancreatic cancer

31 July 2018 | By Dr Zara Kassam (Drug Target Review)

Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...

New drug for ALS ready for clinical trials

26 July 2018 | By Drug Target Review

Previous studies have suggested that a gene therapy drug may be used to treat ALS...

BCX7353 shows hope for hereditary angioedema

26 July 2018 | By Dr Zara Kassam (Drug Target Review)

A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...

New target for chronic inflammation in colorectal cancer

13 July 2018 | By Drug Target Review

IGF-1 activated by p38 may be a therapeutic target

Scientists uncover the mechanism by which cancer cells resist ageing

28 June 2018 | By Drug Target Review

Scientists in the U.S. have found that human lung cancer cells resist dying by controlling parts of the ageing process. The discovery could help us better understand ageing and eventually lead to new treatments for cancer.

ISSCR 2018 to highlight research driving new discoveries and advances in regenerative medicine

8 June 2018 | By ISSCR

Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.

Expert view: Biological therapeutics are becoming more popular, here are the reasons

7 June 2018 | By Dr. Paul Wylie (Head of Applications at TTP Labtech)

For most people, traditional High-Throughput Screening (HTS) represents large automation rigs and large libraries of small molecules screened against drug targets, however, the development of biological therapeutics has been gaining considerable pace for many reasons.

New class of drugs could help tackle treatment-resistant cancers

12 April 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...

Stem cell therapy discovery for age-related macular degeneration

3 January 2018 | By Dr Zara Kassam (Drug Target Review)

Stem cell-derived retinal cells need primary cilia to support the survival of light-sensing photoreceptors...

IONIS-HTTRx lowers deadly Huntington’s disease protein

12 December 2017 | By Dr Zara Kassam (Drug Target Review)

The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial…