news
IONIS-HTTRx lowers deadly Huntington’s disease protein
The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial…
List view / Grid view
Clinical Trials
article
Meeting access challenges with adaptive trial designs
With access challenges even after successful but costly development programmes, the industry is under pressure to speed up the clinical development process and produce more for less. Adaptive trial designs, more collaborative working and data sharing could provide a solution in the area of cancer immunotherapy, says Jacqueline Karmel, principal…
news
ARBs may solve the global antibiotic crisis by 2020
A British biopharmaceuticals company, have developed Antibiotic Resistance Breakers which can restore the original potency against both Gram-positive and Gram-negative bacteria...
news
Scientists identify new treatment for Activated PI3-kinase Delta Syndrome
Scientists have identified a new treatment approach for patients with a rare inherited immune disorder...
news
Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
news
CRISPR-engineered cancer model to test therapeutics
A new technique for modelling leukaemia may aid drug discovery...
news
Three-in-one antibody may protect from HIV-like virus
A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...
news
Therapy proves effective in subgroup of COPD patients
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...
news
DNA sequencing could open up new drug indications for rare cancers
A network of hospitals have systematically collected biopsies from metastatic cancer patients in order to create a global database...
news
Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
news
Novel immuno-oncology treatment for patients with advanced solid tumours
An experimental immuno-oncology treatment will move into early phase clinical trials for patients with advanced solid tumours...
news
Promising therapeutic approach for improving mitochondrial function
Scientists have made progress in the development of products that improve mitochondrial function...
news
Biological bypass shows promise in coronary artery disease
A new gene therapy that targets the heart and requires only one treatment session has been found safe for patients with coronary artery disease...
news
US Phase 2 trial to test targeted drugs in paediatric tumours
Phase 2 trial to explore targeted therapies for children with solid tumours that harbour specific genetic mutations which have progressed during or after standard therapy...
news
Researchers find new genes link to arthritis in bone marrow lesions
Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.