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AI designed, synthesised and validated new drug in 46 days
Researchers have developed a new AI system which was able to discover and then successfully test several new compounds within 46 days.
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Clinical Trials
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Tuberculosis vaccine shows efficacy in pre-clinical trials
Australian researchers have demonstrated the success of a novel TB vaccine in mice, which could provide another treatment option for the disease.
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Blocking kinase could provide treatment for prostate cancer
Researchers have found that inhibiting a kinase in mice leads to the death of prostate cancer cells, providing a potential therapeutic target.
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Genes linked to Alzheimer’s risk have been identified
Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.
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Researchers grow genetically engineered mini livers to study disease
The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.
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New model predicts cognitive decline two years ahead
Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.
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New system enables improved pre-clinical testing of heart drugs
Researchers have extended the life of heart segments from 24 hours to six days, enabling pre-clinical trials to experiment on these new models for longer periods of time.
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Treatment for Lafora disease shows promise in pre-clinical study
A novel antibody-enzyme fusion therapeutic strategy for Lafora disease has shown effectiveness in pre-clinical study mice models.
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Models should be in social conditions for pre-clinical trials, study finds
A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
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New version of HIV vaccine could soon be ready for clinical trials
A promising vaccine that clears an HIV-like virus from monkeys is closer to clinical trial human testing.
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Guide: Questions to ask your human biological specimen provider
The foundations for protecting human research subjects come from the ethical principles surrounding the Belmont report : Respect for persons, beneficence, and justice.
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Gene activity app could reduce live model usage
Researchers have developed an app which displays the effects of diseases in mice models and can be accessed globally.
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First patient enrolled in Parkinson’s treatment study
A trial has begun in the US for the ENT-01 therapy treatment of Parkinson’s, with the first patient enrolled.
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Female animals should be included in trials, new argument proposes
Using exclusively male animals in experiments biases results, argues Rebecca Shansky.
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US company put on notice for marketing unapproved stem cell products
Arizona company claims their products can treat Lyme disease, diabetes, Parkinson’s disease and more, but have not been approved for any use.