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Boltz-1: A new open-source AI tool for drug discovery
MIT's new open-source AI model, Boltz-1, could transform drug discovery by accurately predicting protein structures, offering global access to researchers.
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How AI will reshape pharma in 2025
AI is set to transform drug development in 2025, streamlining processes and opening new possibilities. Learn how this technology is transforming clinical trials and reshaping the pharmaceutical industry.
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Nobel Prize celebrates AI’s role in protein structure innovation
The 2024 Nobel Prize in Chemistry honours AI's transformative impact on protein science, with breakthroughs set to reshape drug development.
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Scientific workflow for hypothesis testing in drug discovery: Part 1 of 3
Explore the step-by-step scientific workflow behind drug discovery, from formulating hypotheses to analysing data, ensuring accurate and reliable results.
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Computational pipeline for personalised cancer vaccine design
16 October 2024 | By
Ludwig Cancer Research researchers have designed and validated a computational pipeline which integrates molecular and genetic analyses.
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Unlocking the potential of smart antibodies
Biolojic Design is redefining antibody therapies by creating “programmable” antibodies that intelligently target well-validated autoimmune and oncology pathways. In this Q&A, CEO and founder Yanay Ofran, PhD, describes Biolojic’s groundbreaking approach, which leverages AI and machine learning to design antibodies capable of adjusting their behaviour based on their biological environment.…
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HIF inhibition: a potential therapeutic approach for cancers
In this Q&A, Curve Therapeutic’s Chief Scientific Officer Professor Ali Tavassoli discusses how dual HIF inhibition could combat solid tumours.
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Using omic data to develop and validate biomarkers of ageing
Researchers highlight the need for considering biomarkers alongside other health outcomes, as well as the need for omic data standardisation.
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Improved CAR T-cell immunotherapy for acute myeloid leukaemia
Researchers have created dual-targeted CARs, which performed better than single-targeted CARs in both in vivo and in vitro experiments.
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Mapping functional states of oncoproteins with AI
Researchers have developed a computational analysis tool which will improve patient stratification and enable personalised medicine.
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Blood test developed that reliably detects NEPC
A new blood panel test reports the tumour fraction and the tumour type of prostate cancer with a high level of accuracy.
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Novel computational model to study cancer dynamics
An advanced computational model enables scientists to study how cancer cells navigate through blood vessels.
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Potential of small molecule therapeutics for Barth syndrome
Novel findings about the tafazzin gene offers a potential new target and drug candidate for Barth syndrome.
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DNA epigenetic changes: a key cause of cancer
Analysis of cells shows many regions in DNA are differentially activated or inactivated in a cancer-specific manner.
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Spectra: new insights to improve immunotherapy treatments
New open-source computational method called Spectra improves analysis of single-cell transcriptomic data.