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CRISPR-Cas12a enables accurate disease diagnostics
DETECTR system allows quick, one-step detection and diagnosis of disease, infection...
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CRISPR
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CRISPR method efficiently corrects DMD defect in heart tissue
Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of mutations that cause DMD...
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New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
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GalNAc-T6 enzyme selectively up-regulated in colon adenocarcinomas
Researchers have identified an enzyme that appears to drive the conversion of normal colon tissue into cancer...
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Uncovering the early origins of Huntington’s disease using CRISPR engineered embryonic stem cells
Researchers have developed a system to model Huntington's in human embryonic stem cells...
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Researchers create first stem cells using CRISPR genome activation
Researchers have turned skin cells from mice into stem cells by activating Sox2 and Oct4 using CRISPR technology...
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CRISPR prevents hearing loss in mice
Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.
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Q&A: Integrated drug discovery panel – your questions answered
Drug discovery from concept to drug candidate has become a collective effort where multi-disciplinary project teams from CROs work with drug companies and academia to deliver clinical candidates, overcoming multi-factorial research obstacles along the way.
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Charles River adds ERS License to CRISPR/Cas9 service offering
Charles River Laboratories International, Inc. announced the expansion of its CRISPR/Cas9 service offering with the addition of a license from ERS Genomics Limited.
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Inhibiting METTL3 destroys AML cells without harming normal blood cells
An unexpected drug target for acute myeloid leukaemia could open new avenues to develop effective treatments against the potentially lethal disease...
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AFM-CRISPR technique used to map DNA mutations
Nanomapping technology may transform the way disease-causing genetic mutations are diagnosed and discovered...
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CRISPR-carrying nanoparticles edit the genome
New delivery system deletes disease-causing genes and reduces cholesterol...
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CRISPR-dCas9 reveals surprising insight into breast cancer development
Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to become abnormal...
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Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
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CRISPR engineered to edit single RNA letters
New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...