news
RASA2 gene make T cells more resilient
New study finds that using CRISPR to block RASA2 gene makes T cells more resilient against cancer.
List view / Grid view
CRISPR
news
Researchers find that CRISPR gene editing can give rise to cell toxicity and genomic instability
Using computational methods, researchers analysed the most popular CRISPR library designed for human cells and found 3,300 targeted spots that show strong toxic effects.
podcasts
Episode 11 – CRISPR with Dr Jakob Haaber, SNIPR Biome & Dr Richard Fox, Infinome Biosciences
Join leading experts as they discuss the wide range of uses for CRISPR, including for therapeutics and biomanufacturing.
news
Scientists map networks of disease-associated immune genes
The new immune gene networks have implications for developing immunotherapies and understanding autoimmune diseases.
article
ELRIG: New modalities in pharmacology and drug discovery
Drug Target Review’s Ria Kakkad recently visited ELRIG and the British Pharmacological Society’s conference on New Modalities in Pharmacology and Drug Discovery which took place in London, UK. This article shares some of the key takeaways from the event.
news
Using organoids to identify drugs for autosomal dominant polycystic kidney disease
Scientists generated kidney organoids and used them to identify potential drugs to treat autosomal dominant polycystic kidney disease.
news
Soft nickases could be the future of safe, effective gene editing
Researchers in the US have developed a new CRISPR method for treating genetic conditions using nickases that they say is safer and more effective.
news
An effective and error-free gene editor
Scientists have developed a new gene editor which uses a modified pair of molecular scissors that make nicks on opposite strands of the DNA at two different points.
whitepaper
Application note: Advancing CAR T-cell therapy with CTS TrueCut Cas9 Protein
Read this free application note where we look at the CTS TrueCut Cas9 Protein, from its detailed quality specifications to its performance in primary T cells.
news
Are we on our way to a one-time treatment for HIV?
Researchers have developed a new technology that could offer treatment for HIV infection through a single injection.
news
Novel CRISPR screen revealed loss of genes in the interferon gamma receptor signalling pathway
A new study has highlighted that the interferon gamma receptor pathway is necessary for CAR T-cell mediated killing in solid tumours.
news
Using CRISPR to improve lung cancer treatments
Scientists have developed CRISPR with a new process that evaluates the impacts of gene edits that alter rather than deleting DNA code.
news
New CRISPR gene-editing technology could lead to better treatments for HIV
Scientists at Northwestern Medicine have developed new techniques in human blood to pave potential paths towards a HIV cure.
news
Novel approach for discovering cancer drug targets
A next-generation spatial genomics technology has allowed scientists to link specific genes to complex tumour characteristics at a scale and resolution not previously possible.
news
Vaccine to potentially protect against disfiguring skin disease developed
Using CRISPR gene-editing technology, scientists have developed a vaccine designed to prevent infection by Leishmania major.