podcasts Episode 16 – Data acquisition of organoids 24 January 2023 | By Drug Target Review Tune into this podcast to hear experts discuss imaging and obtaining data from organoids!
article Transformational vaccines that address global health challenges 23 January 2023 | By Izzy Wood (Drug Target Review) Drug Target Review’s Izzy Wood spoke to Joseph Hernandez, CEO of Blue Water Vaccines, about developing transformational vaccines to address significant health challenges globally.
news Scientists identify therapeutic targets to overcome radioresistance of brain cancer cells 20 January 2023 | By Ria Kakkad (Drug Target Review) A new drug could replace the current standard for treating radioresistance brain cancer by sensitising the cancer cells to radiotherapy.
whitepaper Whitepaper: Neurodegeneration therapeutics discovery 19 January 2023 | By Cell SIgnaling Technology Advance your neurodegeneration research with our broad antibody portfolio, ready-to-use ELISA, and cellular kits to develop new efficacious therapies.
news Researchers develop an all-optical system for testing lab-on-a-chip human hearts 17 January 2023 | By Ria Kakkad (Drug Target Review) A novel all-optical system uses optogenetics, machine vision cameras, and off-the-shelf components to stimulate and image engineered networks of human heart cells.
whitepaper Application note: Real-time kinetic analysis of Akt activity 16 January 2023 | By Sartorius Incucyte® Live-Cell Analysis System Cell signalling through the Akt pathway controls numerous key cellular functions including proliferation, survival, and migration.
article Advancing organ-on-a-chip technology 13 January 2023 | By Tony Portelli (Drug Target Review) Researchers from the University of Pennsylvania have developed a novel organ-on-a-chip technology called OCTOPUS, an optimised device for growing mini-organs in a dish.
news Study identifies gene and proteins that could treat dry eye disease 12 January 2023 | By Ria Kakkad (Drug Target Review) Researchers found that proteins made by stem cells that regenerate the cornea could be new targets for treating dry eye disease.
news Study suggests existing cancer drug may be effective against non-alcoholic fatty liver disease 11 January 2023 | By Ria Kakkad (Drug Target Review) The researchers used single-nuclear sequencing and advanced three-dimensional glass imaging of mice to find new drug targets for non-alcoholic fatty liver disease.
news A promising oral drug delivery platform could replace injections with pills 6 January 2023 | By Ria Kakkad (Drug Target Review) The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.
whitepaper Glossary: Multiplexing 101 – The essential guide 6 January 2023 | By Leica Microsystems What is multiplexed immunofluorescence microscopy imaging?
whitepaper Poster: Antibodies for microglial activation states 5 January 2023 | By Cell SIgnaling Technology Development of novel rabbit monoclonal antibodies to characterise microglial activation states in murine models of Alzheimer’s disease.
news New method precisely locates gene activity and proteins across tissues 4 January 2023 | By Ria Kakkad (Drug Target Review) The scientists argue the technique enables the creation of complex, data-rich “maps” of organs, including diseased organs and tumours, which could be widely useful in pre-clinical research.
article When exhausted, cancer-fighting T cells may switch sides 2 January 2023 | By Dr Greg Delgoffe (University of Pittsburgh), Dr Paolo Vignali (University of Pittsburgh) Using flow cytometry, Dr Greg Delgoffe and Dr Paolo Vignali highlight that low oxygen environment of tumours can prompt exhausted T cells to suppress the immune system instead of combating cancer.
news Researchers generate organoid model for gastroesophageal junction cancer 30 December 2022 | By Ria Kakkad (Drug Target Review) The scientists discovered that dual knockout of genes in organoids grown from human tissue can generate a model of a potential therapeutic target for gastroesophageal junction cancer.
