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Video: Proteomics solutions for drug discovery
Dr. Stokes, Associate Director Proteomics, discusses how proteomic studies can increase effectiveness, speed of target and biomarker identification.
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Disease Research
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ASD-like symptoms in chicks caused by neonicotinoid
Japanese researchers found an ASD-like behavioural impairment in chicks, suggesting a molecular pathway of ASD pathogenesis.
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Novel protein identified that contributes to tau neurotoxicity in Alzheimer’s disease
US researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau, which is primarily found in neurons that appear abnormal in the brains of Alzheimer’s disease patients.
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New MACHETE technique developed to slice into cancer genome
Sloan Kettering Institute (SKI) researchers have developed a new machete technique to slice into the cancer genome and study copy number alterations.
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Highlights from PEGS Europe’s Protein & Antibody Engineering Summit
Drug Target Review’s Ria Kakkad recently travelled to Barcelona to attend PEGS Europe’s Protein and Antibody Engineering Summit. In this article, she shares her highlights from the event.
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Probiotic ‘backpacks’ show promise for treating IBD
US researchers have uncovered the uncapped potential that gut-friendly bacteria has for improving treatments of inflammatory bowel disease (IBD).
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Drug discovery for COPD treatments
In this article, Drug Target Review’s Ria Kakkad shares some of the most recent progress in discovering a drug for COPD, a disease that remains a major challenge in the medical industry.
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Scientists identify neurotransmitter that could help treat Parkinson’s
The study, involving mice, found that the neurotransmitter can act as a break to dopamine.
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Potential secret of viral resistance unlocked
Trinity researchers have discovered the secret to viral resistance, by screening women exposed to HCV.
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Scientists discover the cause of Congenital Hyperinsulinism
A research team at the University of Exeter have found that the unexplored genomic control regions yield the key to finding causes of Congenital Hyperinsulinism.
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Monkeypox mutations cause virus to spread rapidly, evade drugs and vaccines
Researchers show how monkeypox mutations cause virus to replicate, spread faster.
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How ageing triggers Huntington’s disease
A new study found that as patients age, Huntington’s disease gradually impairs the important cellular housekeeping process autophagy, which is responsible for eliminating waste from cells.
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Metastatic potential of cancer cells increased in high viscosity environments
UPF and John Hopkins scientists have discovered how cancer cells exposed to high viscosity environments change their movements to improve their invasiveness and favour metastases.
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Researchers develop and test risk score for pSSNS
Scientists have generated polygenic risk scores for developing paediatric steroid sensitive nephrotic syndrome (pSSNS), a kidney disease in children.