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Findings on pancreatic cancer could improve immunotherapies
Researchers have revealed the immune landscape and microbiome of pancreatic cysts as they progress to pancreatic cancer, providing targets for immunotherapy.
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Disease Research
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The 3D structure of a twinkle protein has been developed for the first time
Researchers have developed a 3D structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.
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Application note: Hyperion+ imaging system
A powerful tool to study complex phenotypes and cellular interactions. Map spatial interactions twice as fast with this second-generation system.
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Scientists generate a mouse embryo model that develops neural tubes
The new mouse embryo model system promises to spur research into developmental health and disease.
webinar
Decoding cancer and inflammation: identifying selective inhibitors of SH2 domains
31 August 2022 | By Eurofins Discovery
Watch our on-demand webinar where our expert speaker will explore the possibilities for designing selective small molecules targeting the SH2 domains of STAT proteins plus more.
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Application note: Quantifying T Cell response in 3D tumour spheroids
Application note: Quantifying T Cell response in 3D tumour spheroids using advanced flow cytometry workflows.
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Engineering cell lines for rare disease research and precision therapeutics
19 August 2022 | By Sartorius
Want to learn about the latest research and development of cell models in rare diseases? Then watch this virtual panel discussion to hear from industry experts.
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Publications review: Applications in infectious disease and immuno-oncology
This publications review overviews advanced flow cytometry applications in infectious disease and immuno-oncology.
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ebook: Immune checkpoint targets for cancer research
Learn about current and emerging immune checkpoint molecules that are being investigated as potential immuno-oncology targets.
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Guide: How to build an effective protein degrader
This guide highlights the four major stages of TPD, the challenges at each step and questions you should ask yourself.
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ebook: The biologics researcher’s guide to dynamic light scattering
Learn about DLS, a powerful method to characterise the purity and aggregation state of your biologics for improved candidate selection.
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Application note: Antibody custom services
R&D Systems offers custom antibody production services to engineer the right antibody to solve your research question with confidence.
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Gene therapy approach shows promise in treating ALS
In rodent models of ALS, the introduced neuroprotective protein slowed disease progression and increased life span.
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Using optogenetics to restore cell function
In a new study, researchers have found that light can be used to naturally balance a cell’s mitochondria.
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An EGFRvIII-targeted immune-based therapy could potentially treat glioblastoma
A T-cell bispecific antibody shows potent anti-tumour activity in preclinical models of epidermal growth factor receptor variant III (EGFRvIII) mutant glioblastoma.
