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Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells
A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.
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Disease Research
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Whitepaper: CAR T-Cell analysis with modular antibodies using SpyTag protein ligation
Here Bio-Rad presents the generation of specific anti-CAR T-cell antibodies to show how CAR T-cell analysis benefits from our modular antibody assembly technology using SpyTag-SpyCatcher protein ligation.
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New discovery could lead to treatment for cardiac hypertrophy
Scientists have identified an important new mechanism that causes the heart’s muscle to thicken which markedly increases the risk of irregular heart rhythms and cardiac hypertrophy.
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Handbook: Flow cytometry
An easy-to-follow guide to flow cytometry that is well suited for researchers new to the technique, or experienced scientists looking for a refresher.
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Drug Target Review – Issue 2 2022
In this issue are articles focusing on a novel stem cell therapy for hearing loss, how a non-linear chiroptical effect could aid drug discovery and the advantages of cryo-electron tomography for imaging research. Also included are pieces on gene therapy, spheroids and genomics.
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New insights into how genetic factors affect body’s immune response in type 1 diabetes
The new study highlights 11 genes which could be considered as potential candidates for novel therapeutics for type 1 diabetes.
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Podcast: Challenges for the bioanalysis of CAR-T Cells
Podcast discussion featuring CAR-T Cell therapy development and reviewing current challenges and future potentials for these cell therapies.
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Mouse study shows gene therapy could fight against rare disease
A new study shows that gene therapy could correct a rare creatine deficiency disorder that commonly results in intellectual disabilities, problems with speech, involuntary movements, and recurrent seizures.
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Guide: How to reduce cost and time by setting up reproducible HTS/HCS with 3D cell culture models
This guide shows how to reduce cost and time by setting up reproducible HTS/HCS with 3D cell culture models with animal-free GrowDex® hydrogels.
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Ultra-powerful brain scanners offer hope for treating cognitive symptoms in Parkinson’s disease
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
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Novel process revolutionises microfluidic fabrication
Researchers have implemented structural colour printing in microfluidic fabrication which creates new pathways for medical diagnostics and miniaturised sensors.
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Thanks to existing vaccines, monkeypox could be containable
Governments outside of Africa have launched limited vaccinations to fight against the rising number of monkeypox cases.
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Novel machine learning technique to develop new drugs
New machine learning models could propose new molecules that have specific properties which could fight certain diseases, doing in minutes what might take humans months to achieve manually.
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Preclinical study highlights an effective combination immunotherapy for liver cancer
Study in mice significantly slowed liver tumour growth and activated anti-tumour immune response, highlighting an effective immunotherapy for liver cancer.
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A novel tool for studying autoimmune diseases related to COVID-19
Researchers have developed a new bioinformatics pipeline that could help investigate the mechanism underlying the development of autoimmune diseases following SARS-CoV-2 infection.
