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Signatures of certain RNA molecules may help improve disease diagnostics
Scientists have found that molecules produced by cells in response to stress may be indicators of various diseases.
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Disease Research
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How to develop the next generation of CAR T-cell therapies
CAR T cells have shown incredible promise in the clinic, but there is still room for advancement. One avenue for improvement is through modification of the CAR design. However, given the number of exchangeable domains, testing all variations can present a hurdle. In this article, Dr Sarwish Rafiq, Assistant Professor in…
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Newborn brain cells provide a possible treatment for epilepsy
Scientists gained new insights into how immature astroglia might contribute to epilepsy, opening research towards developing new anti-seizure medications.
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Almirall announces a new research collaboration with the University of Dundee to develop an innovative treatment for skin diseases
Almirall and University of Dundee announce a collaboration to develop a novel treatment to fully control itch in skin diseases and achieve a prolonged and profound therapeutic effect for patients.
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Bulletin: Utilising the multiparameter capability of the Ze5 Cell Analyser to monitor T cell exhaustion and effects of immunotherapy
Read this bulletin to learn about a Bio-Rad study where they developed and tested a 16-parameter flow cytometry panel applicable to the interrogation of a range of biologically relevant markers of T cell activation.
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The promise of mRNA therapeutics in producing the first regenerative treatment for SUI
Dr Roger Dmochowski, Professor of Urology and Associate Surgeon in Chief for Vanderbilt University Medical Center, discusses the promise of potential new regenerative for Stress Urinary Incontinence.
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Whitepaper: Advancing cardiac drug discovery with iPSC technology
A review of current challenges and goals in cardiac drug discovery and how innovations on human iPSC technology are helping to overcome them.
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Potential origins of scleroderma highlighted in new study
Researchers at the Weizmann Institute of Science have shown that fibroblasts may be a factor in the origin of scleroderma.
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Mystery behind odd-shaped blood cancer cells revealed
Researchers have found that the Lamin B1 mutation causes odd-shaped nuclei in blood cancer cells, which may lead to improved care for leukaemia patients.
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Study highlights the essential role of dendritic cells in immunotherapy
Researchers have discovered how immune system dendritic cells are key to maintaining and regulating response to immunotherapy.
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Drug Target Review Antibodies ebook 2022
This ebook includes articles about antibody-based therapies that could protect against cancer by utilising a patient's memory B cells. Also included is a piece on an intranasally-delivered monoclonal antibody treatment to potentially protect against SARS-CoV-2.
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Research highlights interaction of mycobacteria with red blood cells and its role in lung disease
A new study has found that mycobacteria are associated with red blood cells at lung infection sites, an interaction that has escaped scientists for 140 years.
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Drug Target Review Immuno-oncology ebook 2022
Included in this ebook are articles on how to develop more effective CAR T cells by modifying the CAR design and why recent findings about ferroptosis in cancer cells could enhance immunotherapies.
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First full sequence of a human genome completed
After two decades, researchers have generated the first complete, gapless sequence of a human genome
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Researchers create triple-negative breast cancer organoids
Scientists have opened a path towards triple-negative breast cancer treatment, by creating organoids from tumour samples.
