news
New model yields promising gene therapy for heart condition
Scientists in Japan have developed a credible heart cell model for arrhythmogenic cardiomyopathy and observed a positive response in the condition using PKP2 gene therapy.
List view / Grid view
Disease Research
news
New protein that enables SARS-CoV-2 access into cells identified
Researchers have found that extracellular vimentin facilitates SARS-CoV-2 entry into human cells, presenting a new target.
whitepaper
Whitepaper: How to successfully use iPSCs for disease modelling
Benefits and key considerations of using human iPSC-derived disease models in drug discovery.
news
Organoid system simulates human liver-islet axis in diabetes
Scientists have developed a multi-organoid system from stem cells that can replicate the liver-islet axis in type 2 diabetes.
news
Important Omicron insights to aid treatment success
Knowledge is power – for scientists at least – and thanks to collaborative research from a UK and German university, we now have better understanding of the SARS-CoV-2 Omicron virus, including how it behaves and effective means of treatment.
news
Understanding the tau tangles in neurodegeneration could aid treatment discovery
Representing a breakthrough in better understanding how tau proteins cause neurodegenerative disease, scientists have mapped the tau interactome.
news
Sino Biological establishes new location in Houston, Texas
Sino Biological has announced that its new location in Houston, Texas, is now open, expanding the company geographically.
news
Opportune identification of novel multiple myeloma target
During investigations into the tropical disease Buruli ulcer, researchers have instead identified a promising new avenue for potential treatments for multiple myeloma.
whitepaper
Brochure: Automation drug discovery
Accelerate your drug discovery workflows efficiently and cost-effectively with lab automation solutions from Beckman Coulter Life Sciences.
news
Collaborative research efforts enabled rapid response to Omicron variant
News from the Pasteur Institute in France reports on how multi organisational efforts of numerous research institutes enabled the scientific community to gain key insight into the Omicron variant, facilitating a rapid life-saving response.
article
CRISPR screens and novel drug targets
According to a new study, a metabolic enzyme studied in cancer biology is key for T-cell function, offering a novel target for anti-inflammatory therapeutics. Dr Jeffrey Rathmell and Ayaka Sugiura from Vanderbilt University in the US discuss their study with Drug Target Review and why inhibiting or genetically deleting the…
news
Model insight into blood enzyme Lp-PLA2 could aid cardiovascular health
A new study in the US has used a computer model to reveal the mechanism of action of lipoprotein-associated phospholipase A2 – a biomarker for cardiovascular disease.
webinar
Chasing my Cure: Leveraging serum proteomics to identify novel therapeutic approaches and predictive biomarkers
4 January 2022 | By SomaLogic
Watch our on-demand one-hour session to discover groundbreaking work to advance precision medicine for Castleman disease.
whitepaper
Whitepaper: SARS-CoV-2 Omicron spike protein and antibodies available
Sino Biological has developed recombinant Omicron Spike RBD protein and antibody reacting with Omicron to support the study of Omicron variant.
article
Flow cytometry in drug discovery and development
With a range of tools available to scientists in the field of therapeutic discovery and development, flow cytometry presents an advantageous method to sort cells based on subtle differences. To find out more, Drug Target Review’s Victoria Rees spoke with Dr Peter O’Toole, Head of Imaging and Cytometry and Dr…