Werner syndrome: mechanism behind atherosclerosis elucidated
Researchers have developed a new in vitro co-culture system which enables an in-depth molecular analysis of atherosclerosis.
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Researchers have developed a new in vitro co-culture system which enables an in-depth molecular analysis of atherosclerosis.
Intestinal epithelial organoids highlight a pathway implicated in CD, named major histocompatibility complex (MHC)-I.
The development of a new membrane which better mimics human extracellular membranes will enable more accurate disease research.
Researchers have identified a new biological pathway driving IBD and similar conditions that could be targeted with MEK inhibitors.
A human pancreatic cancer fibrotic barrier model illuminates how targeting the TGFβ/ROCK2/YAP signalling axis could enhance drug delivery.
Researchers discovered that HER2-positive breast cancer drugs must target both HER2 and EGFR receptors to eradicate disease.
Following direct exposure of human CNS tissues to CWD prions, a significant resistance to the propagation of infection was found.
16 May 2024 | By Drug Target Review
In recent years, immunotherapy has emerged as a revolutionary approach in cancer treatment, harnessing the power of the immune system to combat cancer cells. This webinar will explore the latest advancements in immunotherapy research, highlighting breakthroughs, challenges, and future directions in the field. Participants will gain insights, including immune checkpoint…
Heightened insulin resistance in obese men may elucidate the higher prevalence of type 2 diabetes among these individuals.
AptaFluor SAH: A Homogenous, Universal Assay for Histone, RNA, & DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, & NSP14
Stefanie Flückiger-Mangual, Chief Executive Officer, is one of TOLREMO’s scientific founders and an expert in drug resistance in cancer therapy. She is a biomedical scientist and biochemist by training (University of Fribourg and ETH Zurich, Switzerland) and holds a PhD in Molecular and Translational Biomedicine from ETH Zurich. She led…
Researchers discovered that measuring the concentrations of IL-18 in an individual’s blood could estimate future risk of stroke.
Elevated levels of trimethylamine N-oxide levels were a stronger indicator of CKD risk than the well-known risk factors.
Thousands of bile acids have been discovered, providing new insights into how microbes influence distant organ systems.
Tune in to this episode where we discuss the opportunities CRISPR/Cas technology offers to revolutionise drug discovery.