whitepaper Application note: High-content phenotypic profiling using the cell painting assay 11 August 2021 | By Molecular Devices The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
news New research reveals abnormalities in blood vessels of human hearts 11 August 2021 | By Anna Begley (Drug Target Review) A new study has found abnormalities in the blood vessels of human hearts, possibly leading to treatments for cardiac microvascular dysfunction.
whitepaper Handbook: Latest edition live-cell analysis 10 August 2021 | By Sartorius AG The latest edition of the live-cell analysis handbook is a companion guide for live-cell analysis users. Includes discussion of live-cell analysis.
whitepaper Whitepaper: Understanding T Cell phenotype and function 3 August 2021 | By Sartorius AG This whitepaper overviews the importance of understanding T Cell Biology to build better therapeutics, demonstrates use of advanced flow cytometry.
podcasts Episode 2 – SARS-CoV-2 variants with Dr Justin Lee, CDC, Professor Vasan, CSIRO & Dr Chantal Vogels, Yale School of Medicine 2 August 2021 | By Drug Target Review Listen to this podcast to discover how SARS-CoV-2 variants are sequenced and why PCR assays could provide an alternative for resource-constrained places.
webinar The promise of therapeutic camelid-nanobodies 30 July 2021 | By Bio-Techne Watch this on-demand webinar and learn about robust technologies for nanobody drug discovery.
news Farnesol shows potential to prevent and treat Parkinson’s disease 29 July 2021 | By Anna Begley (Drug Target Review) Researchers have added to evidence that farnesol prevents and reverses brain damage linked to Parkinson’s disease in mouse models.
whitepaper Application note: Measure viral-induced cytopathic effects with a quantitative luminescence assay 28 July 2021 | By Molecular Devices Depletion of ATP due to viral-induced CPE leads to a reduction in luminescence signal, enabling quantitation of viral-induced CPE in host cells.
news “Untreatable” cases of cystic fibrosis may be undermined by new therapy 28 July 2021 | By Anna Begley (Drug Target Review) An experimental drug suggests that therapy for currently untreatable cases of cystic fibrosis is “clearly achievable”.
webinar Utilising synthetic DNA technologies for high-throughput antibody discovery and optimisation 28 July 2021 | By Sartorius AG In this on-demand webinar, our expert illustrates the utility of GPCR libraries and explains how to discover potent functional antibodies against multiple GPCR targets.
news Exosome formulation developed for choroidal neovascularisation therapy 27 July 2021 | By Anna Begley (Drug Target Review) An exosome formulation has been created to deliver vascular endothelial-growth factor (VEGF) antibodies for choroidal neovascularisation therapy in models.
news Personalised organoid models may improve immunotherapy treatment 23 July 2021 | By Anna Begley (Drug Target Review) Researchers have used patient-specific tumour organoid models to improve immunotherapy treatments for appendiceal cancer.
news Treg cells could be answer to multiple sclerosis treatments, say scientists 21 July 2021 | By Anna Begley (Drug Target Review) New research has shown that the protein Piezo 1 prevented Treg cells from controlling the effects of inflammation in a multiple sclerosis mouse model.
news Stem cell model demonstrates how COVID-19 infects brain cells 20 July 2021 | By Anna Begley (Drug Target Review) Researchers have developed a 3D “assembloid” that presents a potential entry route of COVID-19 into the brain.
news Non-invasive optical method could provide insight into brain diseases 19 July 2021 | By Anna Begley (Drug Target Review) A non-invasive, label-free optical method can produce high-resolution imaging of cellular brain diseases in vivo.