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Exosome formulation developed for choroidal neovascularisation therapy
An exosome formulation has been created to deliver vascular endothelial-growth factor (VEGF) antibodies for choroidal neovascularisation therapy in models.
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Disease Research
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Personalised organoid models may improve immunotherapy treatment
Researchers have used patient-specific tumour organoid models to improve immunotherapy treatments for appendiceal cancer.
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Treg cells could be answer to multiple sclerosis treatments, say scientists
New research has shown that the protein Piezo 1 prevented Treg cells from controlling the effects of inflammation in a multiple sclerosis mouse model.
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Stem cell model demonstrates how COVID-19 infects brain cells
Researchers have developed a 3D “assembloid” that presents a potential entry route of COVID-19 into the brain.
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Non-invasive optical method could provide insight into brain diseases
A non-invasive, label-free optical method can produce high-resolution imaging of cellular brain diseases in vivo.
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Recognition of phosphohistidine-containing peptides by antibodies
In this article, Dr Rajasree Kalagiri explains research into the use of monoclonal antibodies for the differential recognition of phosphohistidine-containing peptides.
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New spray shown to help heal heart attack damage in rats
A team have developed a minimally invasive exosome spray that helped repair rat hearts after myocardial infarction.
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Metal-based molecule could inhibit build-up of Alzheimer’s peptides
UK researchers have created a metal-based molecule that inhibits the build-up of Alzheimer’s-associated peptide, amyloid-β, in lab tests.
webinar
Scalable solutions for automated sample preparation in label-free compound profiling
14 July 2021 | By Analytik Jena
In this on-demand webinar, based on field experiences with our research partners, Analytik Jena provides an overview of application demands for a reliable sample preparation automation – from a small and easy-to-use workstation, to a fully automated integration solution by Analytik Jena.
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Prenatal editing halts progression of Hurler syndrome in pre-clinical model
US researchers used an AAV9 vector to edit a single base mutation in a prenatal mouse model, halting progression of Hurler syndrome.
whitepaper
Application note: High-throughput IgG quantitation platform for clone screening during drug discovery and development
Every manufacturing process for potential biologics begins with cell line development, whether it’s for clinical trials or a market launch.
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Therapeutic target discovery could improve breast cancer treatments
Research by a team in Canada reveals a promising therapeutic target to counter HER2-positive breast cancer.
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Screening method finds potential drugs to repurpose against COVID-19
Researchers have identified 38 drugs that could be repurposed to treat COVID-19 through a strategy involving virtual screening and cell-based assays.
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Defective proteins found to be potential targets for Alzheimer’s treatments
US researchers have identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that could be used against these targets.
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Newly designed tumour vaccine could prevent cancer recurrence
Scientists have used nanotechnology to develop personalised tumour vaccines which prevented cancer recurrence and metastasis challenges in mouse models.
