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Case study: Parkinson’s disease modelling for drug discovery
The development of a Parkinson’s disease model, using hiPSC-derived neural cells, to assess alpha-synuclein pre-formed fibril-induced toxicity.
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Disease Research
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Cellular Thermal Shift Assays – bringing relevant target engagement to your drug discovery workflow
11 May 2021 | By PerkinElmer
Get the Big Picture and listen to Pharma thought leaders how they view CETSA® and its impact on their Drug Discovery.
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Epithelial cells found to communicate in two distinct ways
Epithelial cell communication depends on the side of the cell, which could have implications for understanding how cancer spreads.
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Computational epitope map of SARS-CoV-2 Spike protein developed
Researchers have produced a computational simulation of the SARS-CoV-2 Spike protein, finding spots that glycans do not cover.
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Lab of the Future to be 50 percent virtual by 2030, survey indicates
Findings from a survey have shown 72 percent of respondents in the life sciences industry think the Lab of the Future will embrace virtual working.
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Genetic profile of skeleton osteocytes mapped for first time
Researchers have revealed which genes are switched on or off in osteocytes, a bone cell found in the skeleton.
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Antibodies cover entirety of SARS-CoV-2 Spike protein, study shows
Researchers have found that over 80 percent of antibodies target sections of the SARS-CoV-2 Spike protein other than the RBD.
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New label-free imaging method created to visualise brain samples
A novel sensitive label-free imaging method has been developed to visualise brain samples using an FxClear-based tissue clearing technique.
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MIS hormone shown to suppress ovarian follicle development
Researchers have shown how the MIS hormone can prevent ovulation in females, making it a potential new form of contraception.
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New 3D lung-on-a-chip model enables study of respiratory diseases
Scientists have developed a 3D lung-on-a-chip model of the distal lung and alveolar structures, enabling the study of COVID-19.
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ebook: Antibody detection for cancer research
Gain more insight into immune-tumor interactions and learn how antibody detection techniques like multiplexing is advancing immunotherapies.
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New imaging method visualises respiratory activity of cell models
Researchers have created a new imaging technique called electrochemiluminescence to visualise multiple spheroids with a single shot.
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Article: Finding a (biomarker) needle in the haystack
Summary of a neurology publication by Alnylam Pharmaceuticals: large-scale protein screening identifies novel biomarker for onset and progression of lethal ATTRv amyloidosis.
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Novel nanopore platform developed to sequence DNA
Scientists have created a new nanopore sequencing platform that can detect the presence of the nucleobases of DNA.
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UK Government to fund £37 million into genomics projects
UK Health Secretary Matt Hancock has announced £37 million of funding for genomics and data projects to support the life sciences sector.