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D614G Spike mutation makes SARS-CoV-2 up to eight times more infectious
A study has shown the D614G mutation in the Spike protein of SARS-CoV-2 makes the coronavirus more transmissible than the original virus from China.
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Disease Research
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RNA sequencing reveals insight into tuberculosis infection
Using single-cell RNA sequencing, researchers have shown that interferon response is correlated with tuberculosis progression.
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Mutations in SARS-CoV-2 Spike could lead to greater infectivity, study shows
Comparing the original SARS-CoV-2 Spike protein with a mutated version, researchers have potentially revealed why the mutated version is dominant.
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Researchers discover process viruses use to block antiviral immune response
A team has revealed that viruses ‘hijack’ a molecular process in the cell, inhibiting the body’s response to viral infection.
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Protein sequences provide insight to SARS-CoV-2 infection, study shows
Research has shown that ACE2 and several integrins containing SLiMs are involved in SARS-CoV-2 infection, presenting new therapeutic targets.
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ebook: Vaccines in the digital age
In this ebook, we’ll see how digitally enabling your organisation can increase capacity and improve vaccine production.
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Scientists reveal four discoveries about early SARS-CoV-2 infection
Researchers studying SARS-CoV-2 at the individual cellular level have made four major discoveries about early infection from the coronavirus.
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Whitepaper: Profiling oncology candidates
Profiling oncology drug candidates through complementary in vitro assays and in vivo models to better understand their potential clinical applications.
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Whitepaper: Automated cell culture and screening
This whitepaper describes the automated culturing of hiPSC-derived cells for high-throughput phenotypic screening, using validated phenotypic assays.
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Flaw found in lab models used to study human blood-brain barrier
Researchers have uncovered a flaw in lab models used to study the human blood-brain barrier and a potential strategy to correct the error.
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Could downregulating the Drp1 protein prevent Alzheimer’s progression?
In this article, we explore the findings of a study that suggests a newly identified pathway, the Drp1-HK1-NLRP3 signalling axis, could be a promising target for therapies to prevent Alzheimer’s disease progression.
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Tissue damage and genetic mutations interact to drive pancreatic cancer, finds study
New research shows tissue damage to cells carrying KRAS mutations induces epigenetic changes that promote pancreatic cancer.
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Study provides insight into muscle wasting in cancer patients
Using a mouse model, researchers found that cancer progression led to fewer skeletal muscle ribosomes, likely explaining muscle wasting.
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Researchers identify how Zika infects foetuses and a potential drug to prevent it
According to scientists, maternal cells act as a reservoir for Zika, enabling the virus to pass from mother to foetus during pregnancy.
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Deletions in SARS-CoV-2 Spike protein drive antibody escape, study shows
Researchers have found that SARS-CoV-2 evades immune responses by deleting parts of its genetic sequence that encode for the Spike protein.
