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Expert view: The importance of accurate synthetic DNA fragments
Innovations in synthesis technology and gene synthesis have become a powerful and valuable means of obtaining genetic material.
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Upstream Bioprocessing In-Depth Focus 2019
This In-Depth Focus features articles highlighting the importance of effective data management strategies as well as the recent trends in upstream bioprocessing.
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Five recent Parkinson’s disease drug target discoveries
This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.
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Researchers identify key mechanism of typhoid toxin
The process of Salmonella typhi to damage DNA has been revealed by researchers at the University of Sheffield which could inform treatments.
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Researchers develop new DNA microscopy technique
The novel method for imaging molecules in cells and tissue samples, called DNA microscopy, could improve knowledge of disease development.
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Uncharted area of genome mapped by advanced imaging
Researchers have mapped a previously uncharted region of the human genome which could lead to tests for certain conditions in the future.
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Telomere damage in cells is caused by runaway mitochondria
Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
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New study reveals causes of stem cell transplant rejection
A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.
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Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
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New discovery could lead to new treatments for Parkinson’s
New discovery makes it possible to design new therapies to replace alpha-synuclein's function in people with Parkinson's disease.
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‘Longevity gene’ could be replicated to fight cardiovascular disease
The so-called 'longevity gene' has been included in animal models, in which it stopped atherosclerosis.
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Secondary structures study could lead to making cancer cells vulnerable
Researchers have used machine learning to discover that the two most widespread DNA structures cause genome mutations that lead to cancer.
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Source of nucleic-acid asymmetry could improve gene therapies
Researchers have analysed the physical origin and biological consequences of DNA-RNA hybrids which could inform gene therapies.
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New technology provides process for precise gene editing
Researchers have presented their new technology for accurately inserting genes into the genome without cutting DNA.
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Autoimmune disorders could be treated with new compounds
New research could lead to novel treatments for autoimmune disorders and sheds light on the causes of autoimmunity.
