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Gene signature holds promise for early detection of active TB

20 June 2018 | By Drug Target Review

A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.

news

CRISPR-Cas9 tool could increase cancer risk

12 June 2018 | By Dr Zara Kassam (Drug Target Review)

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer...

news

p53 gene prevents cancer development

12 June 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have discovered how the most important gene in preventing human cancer, p53, is able to stop the development of lymphoma and potentially other types of cancer...

news

Genomic medicine may one day revolutionise cardiovascular care

30 May 2018 | By Drug Target Review

A new scientific statement summarises the state-of-the-science of genomic medicine...

news

Profiling the genome hundreds of variations at a time

24 May 2018 | By Drug Target Review

A CRISPR-Cas9 high-throughput strategy creates the possibility to rapidly profile and identify genes and DNA sequence variations key to different traits and diseases.

news

NMT molecule provides hope for common cold cure

21 May 2018 | By Drug Target Review

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells...

news

NDF identified as the missing factor in gene activation

16 May 2018 | By Drug Target Review

Scientists find the missing factor in gene activation...

news

A link between Huntington’s disease and rheumatoid arthritis identified

15 May 2018 | By Dr Zara Kassam (Drug Target Review)

Epigenomic analyses may lead to other unexpected findings and novel therapeutic drug targets for many diseases

news

New insights into the origins of mutations in cancer

2 May 2018 | By Drug Target Review

Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...

Scientists generate an atlas of the human genome using stem cells

news

Scientists generate an atlas of the human genome using stem cells

25 April 2018 | By Drug Target Review

Scientists have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease.

news

CRISPR used to edit DNA outside of the cell

23 April 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed a breakthrough CRISPR gene-editing tool, that could allow researchers to quickly and precisely engineer multiple changes to the genetic code...

news

Scientists mine gene responses to existing chemotherapies to facilitate precision cancer treatment

19 April 2018 | By Drug Target Review

Scientists utilise computational biology techniques in a bid to enable doctors to use targeted therapies for cancer patients.

news

New study discovers cancer-relevant protein shield

18 April 2018 | By Drug Target Review

Researchers have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment...

whitepaper

Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking

12 April 2018 | By BMG Labtech GmbH, Carl White (Molecular Endocrinology and Pharmacology), Ethan See (The University of Western Australia), Kevin Pfleger (Dimerix Limited)

In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.

news

An advance for precision medicine

10 April 2018 | By Drug Target Review

Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...

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