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Phages could help to tackle antimicrobial resistance
Researchers have found what triggers bacteria to start the CBASS immune response to counter infections by phages.
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Understanding the genetic origins of disease variation
Researchers, using high-resolution mapping and mathematical modelling, have found mechanisms controlling mutation-driven diseases.
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Y chromosome discovery could advance personalised medicine
Researchers have completely decoded the human Y chromosome, which may result in more effective treatment for digestive disorders.
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Improving ovarian cancer outcomes with artificial intelligence
Researchers have developed an AI based model that is 80 percent accurate in predicting the therapy outcome of high-grade ovarian cancer.
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Cancer and the DNA fork reversal mechanism
Researchers find that polymerase epsilon exonuclease is an essential target for cancer diagnosis and treatments that rely on DNA damage.
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Huntington’s disease: danger of repeated DNA sequences
Scientists find a way to slow the progression of Huntington’s disease by analysing DNA and find the basis of a potential treatment.
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Alzheimer’s genetic variants connected with microglia function
Researchers pinpoint connections of risk variants with microglia functions that are important for Alzheimer’s disease (AD).
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Childhood cancer survivors’ mortality risk
Researchers find genetic explanation for increased risk of developing second cancers.
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Women in Stem with Dr Emily Leproust
This September edition of our Women in Stem series spotlights Dr Emily Leproust, CEO of Twist Bioscience. Dr Leproust began her STEM journey from a background in chemistry, eventually leading her to the forefront of DNA synthesis technology. She co-founded Twist Bioscience in 2013, now a thriving company reporting substantial…
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Engineered immune cells for improved cancer defence
A collaborative team has uncovered a method to extend the functionality of CAR-T cells.
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New research holds significance in regulating T cell function
New research shows T cells use the nuclear receptor RARα not just for gene regulation, but also to trigger cell surface events that activate them against pathogens and cancer.
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Multiomics approach unveils flu severity insights
Some individuals may experience more severe symptoms when infected with the same virus compared to others. The reasons behind this variability are not yet fully understood. While viral factors, such as differences in the virus strain, do play a role, they cannot account for the diverse responses observed among individuals…
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Immunotherapy: antibody set for combating tumours
A recent study sheds light on the potential of artificial DNA structures that, when combined with antibodies, guide the immune system to target cancer cells specifically.
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DNA repair breakthroughs for innovative cancer treatment
This study explores cell survival, the continuous repair of DNA breaks is crucial. Failure to repair DNA effectively can result in mutations, contributing to the development of cancer.
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Precision medicine: exploring the impact of DNA Testing
The potential of precision medicine requires a small shift in perspective, Patrick Short, CEO and co-founder of Sano Genetics, explains in this Q&A.