news New research points to a possible driver of Parkinson’s disease 28 February 2022 | By Ria Kakkad (Drug Target Review) A study has shown how Parkinson’s disease may be driven by cell stress-related biochemical events that disrupt a key cellular clean-up system.
news New study sheds light on drug-resistance mechanism 25 February 2022 | By Ria Kakkad (Drug Target Review) MIT chemists have discovered a possible way to design drugs that could fight against drug resistance.
news Pathway to treat type 1 diabetes revealed in study 8 February 2022 | By Ria Kakkad (Drug Target Review) A new study has identified harmful cellular pathways that prevent insulin production, presenting a drug target for diabetes.
news Tweaked bacteria genes activate heart cells in mice 7 February 2022 | By Victoria Rees (Drug Target Review) Researchers have shown that engineered bacterial genes coding for sodium ion channels could lead to novel gene therapies for electrical heart diseases.
news Multifaceted flu vaccine demonstrates wider protection 2 February 2022 | By Mandy Parrett (Drug Target Review) Scientists at Georgia State University have developed an intranasal influenza vaccine using a new combination of nanoparticles for improved defence against flu strains.
news Novel DNA-free virus-like particles deliver gene-editing proteins to animal models 24 January 2022 | By Victoria Rees (Drug Target Review) Researchers have developed a new drug delivery system using virus-like particles to successfully transport gene-editing proteins in pre-clinical studies.
news Novel nanotherapy offers hope for potential treatment of type 1 diabetes 18 January 2022 | By Nic Losardo (Drug Target Review) Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.
news Nanoparticle delivery of CRISPR enables genome editing of vascular endothelium 6 January 2022 | By Victoria Rees (Drug Target Review) According to researchers, a new method to deliver CRISPR-Cas9 to vascular endothelial cells could be used to treat many diseases, including COVID-19.
news New antibody delivery system could improve precision medicine 4 January 2022 | By Victoria Rees (Drug Target Review) Scientists have developed a metal-organic framework that, when attached to antibodies, improved their targeted delivery in in vitro studies.
news Experimental gel promotes arteriovenous fistula (AVF) formation in rodents 17 December 2021 | By Anna Begley (Drug Target Review) The self-assembling, nanomatrix gel may represent the first effective therapy to promote healthy arteriovenous fistula (AVF) maturation in kidney disease patients.
news Transformable nanoparticles promise advances in tumour treatments 13 December 2021 | By Anna Begley (Drug Target Review) A new study provides an in-depth review on the designs and applications of morphology-transformable nanoparticles to improve cancer therapies.
news Intranasal drug may be the future of depression treatments 12 November 2021 | By Anna Begley (Drug Target Review) Groundbreaking study succeeded in the intranasal delivery of an anti-depressant peptide-based drug to the brain in mouse models.
podcasts Episode 3 – Cell & gene therapy with Dr Sam Wadsworth, Ultragenyx Pharmaceutical & Dr Eric Ostertag, Poseida Therapeutics 1 November 2021 | By Drug Target Review Tune in to this podcast to learn about AAV vectors for gene therapy delivery and engineering CAR T cells against solid tumours.
news 3D printed microneedle vaccine shows promise in animals 19 October 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that a new microneedle vaccine patch was 10 times stronger at generating an immune response in animals than a subcutaneous injection.
news Nanobubbles show promise for delivering anti-inflammation treatments 8 October 2021 | By Anna Begley (Drug Target Review) Nanobubbles known as extracellular vesicles (EVs) were shown to deliver protein drugs in animal models with inflammatory diseases.
