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Combination therapy prevails against BET inhibitor resistance
St. Jude Children's Research Hospital, US, scientists created a new combination therapy method to tackle drug resistance in a type of leukaemia with KMT2A gene rearrangement.
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Drug Delivery
Drug delivery refers to approaches for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
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Under the microscope: The remit of expertise putting nanomaterials to work
Tom Darlington, Senior Director at nanoComposix, discusses scaling up manufacturing of nanomaterials for regulated applications and the rewards of working on biomedical projects.
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Whitepaper: PSMA Protein in the Battle Against Cancer
The PSMA Protein is a new therapeutic hot target. In this article, learn about its growing role in the fight against prostate cancer and beyond.
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Transporting antibodies across the blood–brain barrier to treat Alzheimer’s disease
Researchers have found a way to ensure that new Alzheimer’s medications are delivered to the right place in the body and at the right timepoint in disease progression, so that they have the best effect.
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New self-powered drug delivery system
US researchers have invented a drug delivery technology that has implications for opioid epidemic, cancer treatment, rehabilitation care and more.
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Transformational vaccines that address global health challenges
Drug Target Review’s Izzy Wood spoke to Joseph Hernandez, CEO of Blue Water Vaccines, about developing transformational vaccines to address significant health challenges globally.
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Could drinking green tea, red wine and beer prevent Alzheimer’s?
In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.
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A promising oral drug delivery platform could replace injections with pills
The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.
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Protein Grb10 offers a potential new approach for treating obesity
The researchers found that the protein Grb10 promotes leptin activity in the brain, opening the possibility of developing Grb10-based new approaches to treat obesity.
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Genetic cause of ALS and dementia repaired by RNA-targeting strategy
US scientists have developed a potential medication for the genetic cause of ALS and dementia, that eliminates the mutated segments of RNA.
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Biovac and IVI sign ground breaking deal for the manufacturing of OCV
Biovac signs deal with IVI to develop and manufacture oral cholera vaccine (OCV) for African and global markets.
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The nose-brain pathway: the intranasal administration of drugs to the CNS
Japanese scientists underwent a study exploring trigeminal nerves and how the intranasal administration of the novel glucagon-like peptide-2 can produce antidepressant effects in mice.
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Probiotic ‘backpacks’ show promise for treating IBD
US researchers have uncovered the uncapped potential that gut-friendly bacteria has for improving treatments of inflammatory bowel disease (IBD).
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Novel nasal vaccine strategy could improve COVID-19 protection
Australian researchers have tested a new nasal vaccine in mice, with the potential enhance protection against COVID-19.
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Monkeypox mutations cause virus to spread rapidly, evade drugs and vaccines
Researchers show how monkeypox mutations cause virus to replicate, spread faster.
