news
New insights on the structural biology of medical cannabis
French researchers underwent a structural study showing that THC cannabinoids inhibit a human enzyme called autotaxin.
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Drug Development
article
Could drinking green tea, red wine and beer prevent Alzheimer’s?
In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.
news
Memory loss could be solved using an asthma drug
Dutch researchers, using optogenetic approaches and an asthma drug, discovered that memory loss from sleep deprivation can be retrieved.
news
Novel protein coordinates melanin production
Japanese researchers reported that a key transcription factor “Nrf3” regulates the process of melanin production in mouse and human cells.
news
Protein Grb10 offers a potential new approach for treating obesity
The researchers found that the protein Grb10 promotes leptin activity in the brain, opening the possibility of developing Grb10-based new approaches to treat obesity.
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How to make asthma drugs last longer
US researchers uncover how to make asthma and COPD medication more potent, which could also improve how long they work in patients who need frequent doses.
webinar
Validated bioassays for metabolic & gastrointestinal diseases: Accelerating development of GLP-1 & -2 therapeutics
20 December 2022 | By Eurofins DiscoverX Corp.
In this webinar, we present an approach for building MOA-based, simple, ready-to-use GLP-1 and GLP-2 bioassays and discuss assay validation results from Eurofins BPT.
article
How many drug discovery breakthroughs have we missed?
Today’s drug screening methods use one or two types of data. However, disease biology is not replicable by simple screening models because diseases are complex and heterogenous. However, advanced screening methods that process dozens of data sources at one time have uncovered novel hits that have been overlooked across the…
news
New machine learning model could encode words to kill cancer cells
US researchers, using new machine learning techniques have developed a virtual molecular library of “words” that encode commands to kill cancer cells.
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New ALSV virus discovered in Swiss ticks
Researchers have detected Alongshan virus (ALSV) for the first time in Switzerland in ticks.
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Drug Target Review – Issue 4 2022
A new Drug Target Review issue is now ready to download! This issue features articles which explore how artificial intelligence can enhance screening and ways to find new hits through simultaneous orthogonal screens. Also included are articles on CRISPR, immuno-oncology and RSV vaccines.
news
What parts of a tumour are linked to muscle wasting?
US researchers found that the severity of muscle wasting from cancer is related to the type, size and location of the tumour, in mice.
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Genetic cause of ALS and dementia repaired by RNA-targeting strategy
US scientists have developed a potential medication for the genetic cause of ALS and dementia, that eliminates the mutated segments of RNA.
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Biovac and IVI sign ground breaking deal for the manufacturing of OCV
Biovac signs deal with IVI to develop and manufacture oral cholera vaccine (OCV) for African and global markets.
news
Novel ‘prodrug’ designed to eliminate cancer without harming healthy cells
US researchers discovered in a study in mice that augmented drug eliminates cancer cells without causing toxicity.