podcasts
Episode 4 – LIMS systems with Tyler Pascoe & Matt Gruver, Thermo Fisher Scientific
In this podcast, join Tyler Pascoe and Matt Gruver from Thermo Fisher Scientific as they explore the new Watson LIMS software.
List view / Grid view
Drug Development
news
Experimental gel promotes arteriovenous fistula (AVF) formation in rodents
The self-assembling, nanomatrix gel may represent the first effective therapy to promote healthy arteriovenous fistula (AVF) maturation in kidney disease patients.
whitepaper
Application note: Competitive high-throughput analysis of kinase inhibitor binding kinetics
A microplate-based method for the determination of association and dissociation rate values in high throughput using a kinetic probe competition assay (kPCA).
news
Team identifies lead compound to potentially treat schistosomiasis
Researchers have found a quinoxaline-core containing, non-genotoxic lead compound that could treat schistosomiasis following optimisation.
article
Analysing proteomics data to translate in vivo studies as early as possible
Dr Antal Szalay, CEO and Founder of Ultimate Medicine, explores how the analysis of omics data, especially metabolomics and proteomics, can provide researchers with vital insight that can inform the development of drugs for conditions associated with age.
article
mRNA vaccine technology – a promising platform for novel vaccine development
Dr Pushpanathan Muthuirulan explores why messenger RNA (mRNA) is advantageous for vaccine development and how the COVID-19 pandemic has accelerated its progress within the pharmaceutical industry.
news
New Oxford-GSK Institute aims to unravel complex diseases
GlaxoSmithKline (GSK) and the University of Oxford will collaborate to investigate diseases using technologies such as functional genomics and machine learning.
news
New compound may reduce erratic movements in Parkinson’s patients
Scientists identify a drug candidate to minimise erratic muscle movements, called dyskinesia, associated with Parkinson’s disease.
news
‘Transformational’ machine learning method may speed up drug discovery
Transformational machine learning (TML) learns from multiple problems and improves performance while it learns, potentially accelerating drug discovery.
news
Everest Medicines and Providence to develop Omicron vaccine
Everest Medicines and Providence Therapeutics have started working on a new version of COVID-19 vaccine specifically targeting the new Omicron variant.
news
HAT proteins could unveil new cancer and Alzheimer’s treatments
The new study used cryo-electron microscopy to visualise the structure of a HAT protein and uncover compounds for drug development.
news
Plant-derived antiviral drug could combat Delta variant
A novel antiviral drug called thapsigargin (TG) blocked COVID-19 infection in cells, including all new variants, in a pre-clinical study.
news
ACE2 receptor opens up precision approach against COVID-19
Researchers discover a new precision strategy to hinder the infection of the coronavirus, leading to the filing of a new drug patent.
article
Target safety assessments – identifying risk early
With an ever-increasing emphasis on minimising drug candidate attrition, scientists are focusing on target safety at earlier points in the research process. In this exclusive interview, Drug Target Review spoke with Dr Gordon Baxter, Chief Scientific Officer of Instem, to learn how target safety assessments can enable researchers to quickly…
news
New class of CAR T cells combat previously “untargetable” cancer drivers
The peptide-centric chimeric antigen receptors killed neuroblastoma cells in mice and could potentially expand the pool of immunotherapeutic targets.