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Expert view: Opportunities in flow cytometry
New therapies that direct the immune system to identify and destroy cancer cells, such as CAR-T and immune checkpoint inhibitors, have revolutionised cancer treatment.
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Drug Development
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New strategy developed to speed up drug discovery process
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
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Treatment for polycystic kidney disease shows promising results
A potential treatment for polycystic kidney disease has shown positive results in animal testing.
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Expert view: Advancing antibody discovery with picodroplet technology
It is predicted that there will be 70 new monoclonal antibody (mAb) biotherapeutics available by 2020.
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New biological targets could lead to therapies for drug-resistant cancers
A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
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Expert view: Clarification of cell cultures without centrifugation
Monoclonal antibodies are used in a wide range of applications, such as basic research, biopharmaceutical development and in vitro diagnostics.
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Upstream Bioprocessing In-Depth Focus 2019
This In-Depth Focus features articles highlighting the importance of effective data management strategies as well as the recent trends in upstream bioprocessing.
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Antibodies In-Depth Focus 2019
The articles in this antibodies In-Depth Focus assess the methods used to develop antibody therapeutics and the evolution of this area of medicine to identify drug targets.
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Overcoming resistance in pancreatic cancer treatment
Researchers have developed a new cocktail of drugs that shrink pancreatic tumours in mice by blocking pathways that cancer cells use.
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Proteomic approach reveals metastatic melanoma resistance to therapies
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
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Drug Target Review – Issue 3 2019
This issue includes an investigation into utilising recombinant antibodies for research, a highlight on protein design using computational methods and an examination of the advances in genomic medicine. Also in the issue are articles on next generation sequencing and upstream bioprocessing.
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Five recent Parkinson’s disease drug target discoveries
This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.
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Tuberculosis mutation discovery could lead to better treatments
New gene mutation discovery could lead to more rapid and effective therapies for tuberculosis.
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Potential sepsis prevention in burn patients found with novel approach
A new study has demonstrated the possibility of treating antibiotic-resistant Pseudomonas aeruginosa which causes sepsis in burn patients.
whitepaper
eBook: Acquire and Analyze 3D Cellular Images Like A Pro
This eBook highlights a selection of 3D cell model applications as well as Molecular Devices solutions for acquiring and visualizing quantitative data.