Drug Development

Spined soldier bug can be used to develop new classes of antibiotics

15 November 2018 | By Drug Target Review

Researchers have identified the mechanism by which thanatin attacks the way the outer membrane of Gram-negative bacteria is built...

High throughput screening for deep mining of antibody repertoires, Dr. Stefan Moese, Novartis, Switzerland

9 November 2018 | By Beckman Coulter

In this webinar you learn about a high throughput screening approach for mining of antibody repertoires in the context of biologics drug discovery.

Making old antibiotics work better using r8

7 November 2018 | By Iqra Farooq (Drug Target Review)

A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...

Charles River to present collaborative methods at Neuroscience 2018

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...

Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...

Paclitaxel acting as an immune response modulator

26 October 2018 | By Drug Target Review

Brazilian researchers have discovered that a drug widely used as for chemotherapy also acts as an immune response modulator...

Better drug delivery through the blood-brain barrier

19 October 2018 | By Iqra Farooq (Drug Target Review)

Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue...

Estradiol exerts anticancer effects in triple-negative breast cancer

5 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer...

Exploring quality of life for stoma patients

4 October 2018 | By Drug Target Review

There are many people with a stoma living in the community in the UK.  A commonly reported problem with living with a stoma is a poor quality of life because of uncertainty and doubts in the mind of the person with a stoma. The focus of this article is reviewing…

Alpaca immune system reveals a potential treatment for cancer 

3 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...

PSD-95 molecule reveal potential treatment for stroke patients

3 October 2018 | By Drug Target Review

A novel hybrid approach has revealed a 3D structure of a protein fragment that could serve as a drug target in treating stroke patients...

DNA vaccine shows promise for cancer immunotherapy

28 September 2018 | By Dr Zara Kassam (Drug Target Review)

DNA vaccine optimised to cross-react with several MAGE-A isoforms generates a robust immune response and antitumour activity in a pre-clinical model of melanoma...

‘Paintable’ chemotherapy for melanoma shrinks tumours

27 September 2018 | By Iqra Farooq (Drug Target Review)

A hydrogel incorporating transfersomes and chemotherapy drugs incorporated with some intravenous medication may be the best treatment for melanoma...

Agilent Technologies

New drug Metavert blocks growth of pancreatic cancer in mice

25 September 2018 | By Drug Target Review

Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.