Drug Development

Beckman Coulter, Inc.

Scientists show combined immunotherapy treatment is effective against advanced melanoma

28 August 2018 | By Drug Target Review

Study in the U.S. demonstrates successful treatment of advanced melanoma and metastatic cancer using a new bacteria-like agent combined with an immunotherapy drug.

New lead for Alzheimer’s research proposed

15 August 2018 | By Drug Target Review

Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...

Pushpanathan Muthuirulan

13 August 2018 | By

Research Associate, Harvard University

Combination therapy may be useful against resistant bacteria

13 August 2018 | By Drug Target Review

The team found that colistin worked well with protein synthesis inhibitor antibiotics, which alone have no activity against Gram-negative bacteria...

Injecting VIP into the eye improves corneal transplant survival

13 August 2018 | By Drug Target Review

Results using mouse models suggest that vasoactive intestinal peptide may provide a new method of improving the outcomes of corneal transplant surgery...

Novel vaccine approach proves powerful against Zika virus

9 August 2018 | By Drug Target Review

VSV acted as a vehicle to deliver the genes of some proteins from the Zika virus into mouse models, leading to immunity build up in the mice...

‘Drug cocktails’ could strengthen targeted cancer therapies

7 August 2018 | By Drug Target Review

"Targeted therapies have revolutionised cancer treatment by targeting fewer components within a human cell, thereby promising better efficacy..."

pH imbalance in astrocytes may lead to Alzheimer’s disease

6 August 2018 | By Drug Target Review

The researchers found that 10 of the 100 most frequently down-regulated genes were connected with proton flow in the cell...

Potential peptide drug could treat liver cancer effectively

2 August 2018 | By Drug Target Review

Researchers have discovered that FFW and Sorafenib used together could reduce the growth of Sorafenib resistant hepatocellular carcinoma tumours...

D-PDMP reverses hair loss and skin damage linked to fatty diet

2 August 2018 | By Dr Zara Kassam (Drug Target Review)

In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...

Monoclonal antibodies produced by new cell lines hope to improve drugs

1 August 2018 | By Drug Target Review

Many biopharmaceutical companies look to produce biosimilars soon, since the patents on the original mAb expire over the next few years...

AI system designs drugs from scratch

1 August 2018 | By Dr Zara Kassam (Drug Target Review)

An artificial-intelligence approach created can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates...

CBD improves survival rates of mice with pancreatic cancer

31 July 2018 | By Dr Zara Kassam (Drug Target Review)

Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...

New drug for ALS ready for clinical trials

26 July 2018 | By Drug Target Review

Previous studies have suggested that a gene therapy drug may be used to treat ALS...