Drug Discovery Processes

Atg2 tethers pre-autophagosomal membranes to endoplasmic reticulum

23 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers at Tokyo University have investigated the role of the Atg2 protein in the process of autophagy to aid drug discovery into neurodegeneration...

Single molecule fluorosequencing to transform biological research

22 October 2018 | By Iqra Farooq (Drug Target Review)

Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...

Protein mTOR regulated by Src in cancer growth

19 October 2018 | By Drug Target Review

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified a connection between cancer proteins mTORC1 and Src...

Application note: Orthogonal approaches for studying bacterial biofilms using photometric detection

19 October 2018 | By Thermo Fisher Scientfic

This application note aims to demonstrate the benefits of using orthogonal approaches for studying Staphylococcus aureus biofilms—in particular, their susceptibility to antimicrobial agents...

Investigating tumour microenvironments for more effective treatments

17 October 2018 | By Iqra Farooq (Drug Target Review)

Tumour microenvironments give insights into more effective therapies against lung cancer, a bigger killer than colon, prostrate and breast cancers combined...

Immunotherapy targeting blood protein fibrin

16 October 2018 | By Iqra Farooq (Drug Target Review)

Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...

RNA molecule nc886 could unlock innate immunity

15 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified that the RNA molecule nc886 begins a series of events that leads to the destruction of viruses...

Immunotherapy could cure advanced pancreatic cancer

11 October 2018 | By Iqra Farooq (Drug Target Review)

Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...

Elrig 2018: Drug discovery using small and large molecules

9 October 2018 | By Iqra Farooq (Drug Target Review)

The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...

Super-resolution microscopy builds multicolour 3D images from 2D

1 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have developed a method of exploiting fluorescence in microscopy to generate 3D images of organelles and structures within cells from 2D images...

Amazonian plant provides anti-tumour activity

1 October 2018 | By Iqra Farooq (Drug Target Review)

A plant from the Amazonian region of Colombia has shown anti-tumour properties against human liver cancer cells, but not against healthy cells...

Agilent Technologies

Amyloid beta – a good therapeutic target?

19 September 2018 | By Iqra Farooq (Drug Target Review)

Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...

ELRIG UK Drug Discovery 2018 Event

19 September 2018 | By ELRIG

ELRIG’s (European Laboratory Research & Innovation Group) Drug Discovery meeting, will take place at ExCeL, London, UK, located in the heart of the city, from 9 -10 October 2018...

Synthetic biology in drug discovery

13 September 2018 | By Dr Tim Brears - Chief Executive Officer - Evonetix

Synthetic biology is broadly defined as the design and construction of novel artificial biological pathways, organisms or devices; or the redesign of existing natural biological systems.1 It brings together a range of disciplines and skills, from biology and chemistry to computing, bioinformatics and engineering.