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Drug Discovery

 

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.

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Artificial intelligence: a great crash of hype into reality

30 January 2023 | By

Technology is infamous for falling into a hype cycle, with its peaks and valleys of exaggerated expectations and disillusionment — AI-driven drug discovery is no exception. In this article, Aaron Daugherty, Vice President Discovery at Aria Pharmaceuticals, highlights how the industry can use AI to transform research.

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On the CRISPR horizon: democratising access to genome-editing technologies

16 December 2022 | By ,

Dr Douglas Ross-Thriepland and Dr David Walter, from the Functional Genomics Centre (FGC) – a joint venture between Cancer Research UK’s (CRUK) drug discovery engine, Cancer Research Horizons, and AstraZeneca – speak to Drug Target Review about their work. The centre’s focus is on genetic screening; cancer models; CRISPR reagent…

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Activity-directed synthesis: a structure-blind, function-driven molecular discovery approach

16 December 2022 | By

An autonomous strategy for molecular discovery could enable the exploration of a far broader chemical space than is possible with conventional approaches. In this article, Niamh Morris from Rosalind Franklin Institute outlines why activity-directed synthesis (ADS) could be the answer, providing examples of how this technique has the potential to…