BT13 molecule shows promise for halting Parkinson’s
A molecule has been shown to increase dopamine levels in the brains of mice, offering hope for stopping the progression of Parkinson’s.
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In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
A molecule has been shown to increase dopamine levels in the brains of mice, offering hope for stopping the progression of Parkinson’s.
Alderley Park has announced the opening of Glasshouse, its work space for tech enterprises looking to work collaboratively in drug discovery.
Here, the benefits of collaborating in drug discovery are explored through the strategic alliance between ELRIG and the British Pharmacological Society.
Using an innovative approach to create a model organism, scientists have translated human research into a murine model which they say more accurately reflects coeliac disease.
An innovative chimeric vaccine containing an Ebola gene that helps the virus evade the immune system has been used to selectively target and kill glioblastoma in mice.
A new technology developed by scientists combines small molecule screening methods with machine learning algorithms to identify novel antibiotics that inhibit ribosomes.
The carbon hydrogen functionalisation process could be used to make 3D scaffolds for pharmaceutical compounds, say researchers.
Research into the structure of the drug-integrin complex has enabled the creation of drugs which inhibit integrin as effectively as currently used compounds, without causing excessive bleeding.
Research has shown that human metapneumovirus uses RNA methylation to hide from the immune system and that knocking out this methylation creates a mutant strain which acts like a vaccine.
A study has shown that inexpensive nanoparticles can effectively inhibit PD-L1 in cancer cells in the lab and work as well as antibodies, providing a potential alternative immunotherapy.
A study has identified a protein complex elevated in PTSD patients and developed a peptide to disrupt it, preventing the recall of fear memories in early tests and paving the way for new therapies.
Researchers have discovered that pancreatic cancer cells secrete IL-1β to suppress the immune system and suggest antibody treatments as a therapy for pancreatic ductal adenocarcinoma.
Research suggests that over half of the total $5.2bn investment for artificial intelligence in pharma went to drug design applications in 2019, but overall investment is slowing.
The two organisations have entered into a two-year alliance to improve scientific exchange in the drug discovery industry.
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.