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Hidden culprit in heart failure discovered
A study has identified that PI3K alpha could be the culprit of heart failure, as it binds to gelsolin, suppressing it and preventing it from working...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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UCLA researchers correct mutation causing IPEX
A stem cell therapy rectifying the FoxP3 gene has been developed to treat IPEX, and has virtually cleared symptoms of the condition in mice...
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Two-antibody cocktail could treat Ebola in one dose
A study has described a two-antibody cocktail medication that has been successful in vivo italics trials and could treat Ebola in one dose...
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Whitepaper: The most important mouse in the world: the utility and applications of C57BL/6 models
Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.
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‘Activating’ the immune system against cancer
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
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Whitepaper: Application of CRISPR/Cas to the generation of genetically engineered mice
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.
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Inhalable mRNA could treat lung disease
An inhalable mix of a polymer and mRNA molecules, used to produce luciferase, could be the method of treating lung diseases in the future...
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Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
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Triple-negative breast cancer could be treated using experimental treatment
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
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The mysterious functions of the PCSK9 protein
Researchers have described the methods used to build a model of the 'druggable' PCSK9 inhibitor and detailed how it works...
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Potential drug targets found by muting large silent genes
Streptomyces bacteria has been used to identify compounds that could lead to the production of drugs to treat various conditions...
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Drug targets for Dengue, Zika and Ebola viruses
US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…
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Vaccine could combat opioid addiction and reduce deaths
Researchers have developed a vaccine to combat the opioid epidemic and to prevent deaths, with possible applications of the vaccine in many areas...
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Ebola-fighting protein found in the human body
A study has found that the human protein, RBBP6, helps fight Ebola virus by interfering with the virus replication cycle…
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Ingestible capsule controlled wirelessly could treat diseases
Researchers have designed a drug delivery capsule that can stay in the stomach for up to 1 month, and could sense and treat infections...