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In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
SMi Reports: 8th Annual Orphan Drugs and Rare Diseases Conference to bring together pharmaceutical companies, non-profit organisations and orphan drug developers to explore alliances and facilitate progress.
Drug discovery is a lengthy process that proceeds through several stages. High-throughput screening (HTS) utilising whole-cell-based screening assays plays a fundamental role as a starting point for identifying novel compounds in the drug discovery process.
Autophagy is an important process to maintain cellular homeostasis and function.1 Basal levels of autophagy are essential for most cells to remove unwanted protein aggregates and damaged organelles in order to prevent diseases.2 However, sometimes cells are unable to maintain physiological stability as a consequence of altered autophagy, which leads…
The neutrophil nanosponges can absorb and neutralise cytokines which play a role in the development of rheumatoid arthritis...
Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...
Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…
Venoms are continually being researched as potential chemicals for medicinal therapeutics to treat autoimmune diseases and diabetes...
Researchers have found that Matcha green tea has properties to combat breast cancer stem cells...
Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...
An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...
A team of researchers have identified vitamin B3 can increase levels of NAD+, which is decreased in those with acute kidney injury...
The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...
Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
